Generic Name(s): Ondansetron
Drug Class: Serotonin antagonists
Treats: Chemotherapy side effects
Zuplenz (Ondansetron) is a medication in the drug class of 5HT3 receptor or serotonin antagonists. Zuplenz works by blocking the action of chemicals in the body that can trigger nausea and vomiting caused by cancer therapy. Zuplenz is usually applied on top of the tongue where it will dissolve in 4 to 20 seconds and then swallowed with saliva.
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Zuplenz is basically used along with other medications to prevent episodes of nausea and vomiting caused by cancer drug treatment such as chemotherapy and radiation therapy. Furthermore, Zuplenz may be used to put a patient to sleep before surgery. Zuplenz works by blocking one of the body's natural substances referred to as serotonin that triggers vomiting. Zuplenz may be given to chemotherapy patients suffering from a variety of different cancers. Below you will find the uses of Zuplenz.
- Chemotherapy side effects
Dosage of Zuplenz depends on the individual and the condition being treated. You should always use medication precisely as your doctor prescribes it. Below you will find a typical dosage of Zuplenz. For prevention of nausea and vomiting during cancer chemotherapy
- For adults give the oral soluble film of 24 mg successively as three 8 mg films 30 minutes before the start of the chemotherapy. Each film should be completely swallowed before giving the next film.
For Prevention of nausea and vomiting caused by radiotherapy
- For adults give one 8mg film three times a day, In cases of total body radiation, single high-dose fraction radiotherapy to the abdomen and daily fractionated radiotherapy to the abdomen give one 8 mg oral soluble film 1, 2 hours before radiotherapy, with other doses every 8 hours after the first dose for each day radiotherapy is given.
Zuplenz Side Effects
Like any drug, Zuplenz may cause side effects. If you experience any severe or persistent side effects, you should contact your doctor immediately. Mild side effects should dissipate with time and do not require medical attention. Below you will find a list of side effect associated with Zuplenz. Note that not all possible side effects are listed.
- Fast heartbeat
- Shortness of breath
- Body weakness
- Decrease in urination volume
- Painful urination
- Arm, back or jaw pains
- Chest tightness
- Dry mouth
- Increased thirst
- Loss of appetite
- Mood changes
- Loss of bladder control
- Skin rashes
- Numbness of feet
Like any drug, Zuplenz may interact with other drugs and substances. Drug interactions may cause an increased risk of side effects or change the way your medication works. You should tell your doctor about any medications you are currently taking, including over the counter drugs. Herbal supplements and vitamins may also interact with Zuplenz. Below you will find a list of drugs that may interact with Zuplenz. Note that not all possible interactions are listed.