Von Willebrand Disease Treatment, Drugs, Causes, Symptoms, and Diagnosis

Von Willebrand Disease is a bleeding disorder that affects the blood clotting system. The condition is characterized by excessive or extended bleeding. The condition is mostly traced back to the family lineage, and thus it is mostly categorized as an inherited disease. This means that it is passed from the parents to their children. But in rare cases, it can develop later in life. The patients suffering from this disease usually have a deficiency of von Willebrand factor protein which is a crucial component in the blood-clotting process. The disease can be categorized in three types: type 1 VWD, type 2 VWD and type 3 VWD.

Von Willebrand Disease Drugs

  • Desmopressin
  • Antifibrinolytic
  • Aminocaproic acid
  • tranexamic acid

 

Von Willebrand Disease Symptoms

Like any other medical condition, von Willebrand Disease can easily be detected by its symptoms. The symptoms can also be used to determine the type of the von Willebrand Disease (VWD) the patient is suffering from. Here are some of the main VWD symptoms:

  • Large bruises from minor bumps or injuries
  • Prolonged bleeding after a dental procedure
  • Heavy or prolonged menstrual bleeding
  • Heavy bleeding after a cut or other accident
  • Blood in your stools caused by bleeding in the intestines or stomach
  • Blood in your urine- caused by kidneys or bladder bleeding.
  • Heavy bleeding after surgery
  • Frequent and hard-to-stop nosebleeds
  • Severe bleeding episode for any reason

Von Willebrand Disease Causes

Von Willebrand Disease can be caused by various factors. As an inherited disease, the parent will pass the gene to the children and they will grow with the condition. If only one parent carries this gene, then the patient will have the type 1 and type 2 VWD. These two types of Von Willebrand Disease are not that severe and they can easily be controlled. If the patients have the gene from both parents, then they will be suffering from type 3 VWD which is very dangerous. The patient may also develop the condition later in life and this is referred to as the acquired Von Willebrand Disease.

Von Willebrand Disease Diagnosis

Von Willebrand Disease is hard to diagnose, especially type 1 and type 2 VWD. These two conditions are hard to detect since the patient may not show many of the VWD symptoms. Most of these two conditions are diagnosed after the patient show heavy bleeding after a surgery or other trauma. Otherwise, it will be almost impossible to detect them when the patient is normally operating. In the case of the type 3 VWD, the child will show serious bleeding problems at early stages of life. Physical exams and tests can also be used to determine whether you have the condition or not.

Von Willebrand Disease Treatment

Von Willebrand Disease treatment is based on the type of that you are suffering from. There are many ways through which this condition can be treated. through tests must be run on the patient to determine the type the von Willebrand Disease that they are suffering from Medicines like the desmopressin and antifibrinolytic are very effective in treating VWD. Use of medicines will achieve the following:

  • Increase the amount of factor VIII and Von Willebrand factor in the blood. This will improve the clotting process.
  • Replace the Von Willebrand factor
  • Preventing the breakdown of the blood clots
  • In female patients, they control the heavy menstrual bleeding