Syprine is a chelating agent belonging to a class of drugs known as antidotes. Chelating agents are capable of removing heavy metals in the body such as mercury, copper, and lead. Syprine is used in the treatment of Wilson"s disease among patients who cannot be administered penicillamine. Syprine works by binding itself to copper to help in removing this metal from the blood.
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Patients who suffer from Wilson"s disease and cannot take penicillamine may be treated with Syprine. Wilson"s disease is a common inherited disorder associated with copper metabolism. It results from the inability of the copper metal to be excreted from the body because the excretory pathways are blocked. If the body cannot naturally excrete copper metal, it will cause toxicity to occur as more of this metal is retained in the blood. A first-line treatment may be applied using penicillamine. Patients who cannot tolerate penicillamine are prescribed Syprine. Below you will find the uses of Syprine.
- Wilson"s disease
Dosage of Syprine depends on the individual and the condition being treated. Syprine is administered orally on an empty stomach. You may want to take it at least an hour before you have your meal or two hours after having a meal. The capsules should not be opened or chewed and should be taken with water. During the first month of use, you may want to monitor your temperature. Below you will find a typical dosage of Syprine.
- Adults and children over 12: 750-1250 mg/day is taken and divided into 2 or 4 portions
- The maximum dose should not exceed 2000 mg per day
- Children under 12: 500 to 750 mg is administered orally on an empty stomach, in 2 to 4 doses
- Should not exceed 1500 mg in a day for pediatric use
Syprine Side Effects
Taking Syprine might cause side effects. Not all people may show all the side effects associated with Syprine. The effects may be mild or even severe. If mild side effects persist for long and they become discomforting, you can contact a doctor. Less serious side effects include;
- Skin flaking or thickening
- Loss of appetite
- Muscle spasms
- Skin rash
If you develop any of the below serious adverse effects, visit a healthcare provider immediately:
Like any drug, Syprine may interact with other drugs and medication. Sometimes, doctors combine medications in treating diseases and other conditions even if there are interactions. However, the risk of combining such drugs is evaluated against the benefits. Syprine may interact with some drugs. If you have other medicines you might be taking, tell your doctor before you start a Syprine treatment regime. The below list shows some of the drugs that may interact with Syprine, but this may not be a complete list.