Somatostatin Analogues Drug Class

Somatostatin Analogue hormone is used to inhibit the growth hormone from being released from the anterior pituitary as well as glucagon and insulin that is produced in the pancreas. Somatostatin is produced by both hypothalamus, gastrointestinal, and pancreas. Somatostatin is also responsible for reducing most of the gastrointestinal hormones, as well as gastric acid and secretion by the pancreas. It can be used to reduce the blood flow from the abdominal; it is for this reason that the hormone is used to minimize bleeding from esophageal varices. It is one of the most effective therapies that is available for the treatment of acromegaly.

Somatostatin Analogues Drugs

Those using somatostatin for their treatment use one of these drugs:

Somatostatin Analogues Uses

Somatostatin analogs do several things for the body, it slows down production of hormones including the gut hormones. It reduces that rate at which stomach and bowel are emptying; it is used to control how hormones are being released by the pancreas, and reduces or stops the release of hormones used for growth. If you are suffering from Carcinoid syndrome, you might be given somatostatin to be part of treatment. Since somatostatin works by reducing the rate at which hormones are being produced, especially serotonin and the growth hormone, they can be used for shrinking the tumor.

Somatostatin Analogues Side Effects

Somatostatin analogues do not have many or severe side effects. If you are diabetic and using this medication you need to check the levels of blood sugar. There is likelihood that you might need less insulin and diabetic tablets. If you are suffering from octreotide for a long time chances are that you might develop gallstones. It is important that you have an ultrasound done in your gallbladder before using the treatment and semi-annually from then henceforth. Over 10% of people who are having octreotide stand a chance of having gallstones, though the symptoms of gallstones are rarely seen. A few of the common side effects include:

  • Pain in the stomach
  • Feeling tired
  • Sick
  • Reduction of appetite
  • Feeling bloated
  • Soreness at injection site
  • Diarrhea
  • Changes in blood sugar levels

Somatostatin Analogues Interactions