Soft Tissue Sarcoma Treatment, Drugs, Causes, Symptoms, and Diagnosis

Soft Tissue Sarcoma are a group of cancers that affect the tissues that surround, connect and support other body organs and structures. Some of the tissues that can be affected by Soft Tissue Sarcoma include ligaments, fat, tendons, muscle, deep skin tissues, and blood vessels. Soft Tissue Sarcoma can develop in many parts of the body such as the trunk, arms, and legs.


Soft Tissue Sarcoma Drugs

  • Imatinib (Gleevec)
  • Pazopanib (Votrient)
  • Sunitinib (Sutent)
  • Regorafenib (Stigvara)


Soft Tissue Sarcoma Symptoms

Different people have different signs and symptoms of Soft Tissue Sarcoma. Most times, Soft Tissue Sarcoma does not show any symptoms in the early stages. Different parts of the body have different symptoms. For example when a symptom starts:

In the back wall inside the abdomen, they may have symptoms such as:

  • Pain
  • Bleeding or blockage of the bowels or stomach
  • The tumor may grow large enough for them to be felt in the abdomen

On the arms or leg:

  • It may hurt, but it does not usually hurt
  • Over a period of weeks to months you may notice a lump growing


Soft Tissue Sarcoma Causes

When cells multiply uncontrollably, they form tumors, and that is when cancer develops. It is not clear what causes Soft Tissue Sarcoma. However, there several factors that are known to increase the risk such as:

  • Previous radiotherapy – radiotherapy from a different type of cancer develop Soft Tissue Sarcoma.
  • Age – Soft Tissue Sarcoma is common in middle-aged or elderly people but can occur at any age.
  • Exposure to certain chemicals – exposure to certain chemicals such as dioxins and vinyl chloride has been linked to increasing rates of Soft Tissue Sarcoma.
  • Certain genetic conditions – there are genetic conditions that are associated with Soft Tissue Sarcoma such as retinoblastoma and neurofibromatosis type 1.


Soft Tissue Sarcoma Diagnosis

If there is any chance that you have Soft Tissue Sarcoma, your healthcare provider will refer you to some hospital tests to check for Soft Tissue Sarcoma. The diagnosis that you will get will be based a physical examination, your symptoms, and the result of:

  • Imaging test – there are several scans such as magnetic resonance imaging (MRI) scan that can be carried out to asses Soft Tissue Sarcoma.
  • A biopsy – this is where you use a needle to get a sample of suspected cancerous tissue or during an operation then taken to a laboratory for analysis and testing.
  • If it is confirmed that you have Soft Tissue Sarcoma, the tests will also helpful in telling how far cancer has spread and how aggressive the cancer is.


Soft Tissue Sarcoma Treatment

If your health care provider finds that you have Soft Tissue Sarcoma, your team of nurses and specialist doctors will help you decide on the best treatment. There are several factors that are considered when choosing a specific kind of treatment that depend on several factors. Some of these factors include:

  • Surgery – when Soft Tissue Sarcoma is detected in the first stage, surgery will be the main treatment.
  • Radiotherapy – when treating Soft Tissue Sarcoma, you may use radiotherapy after surgery to get rid of any remaining cells. Radiotherapy may also be used before surgery to make it easy to remove a tumor.
  • Chemotherapy – Chemotherapy may be used in the same way as radiotherapy before surgery to make a tumor easier to remove or shrink it.