Salsalate belongs to the class salicylate. Salsalate has a harmless effect on the cyclooxygenase enzyme hence decreases the production of chemical inflammatory signals in the body. Salsalate is used to treat inflammatory disorders such as rheumatoid arthritis or non-inflammatory diseases such as osteoarthritis. Salsalate is also used to treat diabetes mellitus.
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Salsalate is used to reduce pain and inflammation caused by such conditions of rheumatoid arthritis and osteoarthritis. Salsalate is an anti-inflammatory medication that helps to treat patients with minor stomach bleeding or upset. Salsalate is also recommended as painkiller for people with spinal disk protrusion. Salsalate can lower insulin resistance hence it is used in the treatment of type 2 diabetes mellitus. Salsalate anti-inflammatory property may reverse the chronic inflammation thought to be the cause of diabetes in the obese. Salsalate works by reducing the levels of prostaglandins, chemicals produced by the body responsible for pain fever and inflammation.
- Rheumatoid Arthritis
Salsalate should be taken as prescribed by the physician. Under dose or overdose of Salsalate is harmful and may be associated with several health problems. Salsalate is prescribed according to the disease one is suffering from. Note, the below doses are an average dose and may differ from one individual to another.
- Adult Dose for Osteoarthritis 3000 mg orally daily, given as two doses of 2x750 mg tablets or two doses of 3x500 mg tablets or three doses of 2x500 mg tablets.
- Adult Dose for Rheumatoid Arthritis 3000 mg orally daily, given as two doses of 2x750 mg tablets, two doses of 3x500 mg tablets or three doses of 2x500 mg tablets.
Salsalate Side Effects
Salsalate, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Salsalate, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
- Bloody stools
- Blood in urine
- Increased urination
- Chest pain
- Hearing loss
- Peeling skin
- Ringing in the ears
- Stomach pain
- Shortness of breath
- Weight gain
- Body swelling
- Liver problems
- Bruising or bleeding
Some medical conditions or drugs may interact with Salsalate. Tell your doctor if you have any medical conditions, especially if any of the following apply to you: if you are expectant or lactating, if you are using other medication from authorized or unauthorized source, or if you are eating food that reacts with Salsalate, if you have allergies to Salsal, if you have kidney or liver problems. These conditions may have a significant effect with Salsalate. Some medications that may interact with Salsalate include: