Drug Class: Heparin antagonists
Treats: Excessive bleeding
Protamine Sulfate is aspecial drug that is used as a heparin antagonist. Protamine Sulfate is mostly prescribed to the patients that have been diagnosed with excess bleeding in mostly during surgical operations. Protamine Sulfate is an anticoagulant that treat severe heparin overdose. Protamine Sulfate is supplied in the form of a solution and should be administered intravenously.
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Protamine Sulfate Uses
Protamine Sulfate is an anticoagulant that helps in controlling excessive bleeding. Protamine Sulfate prepared from the sperms of mature species of fish such as salmon.
Protamine Sulfateis formulated with an anti-heparin that helps in the clotting of the blood to reduce excessive bleeding. Heparin is a chemical substance in the body that inhibits blood clotting to promote bleeding. Protamine Sulfateworks by lowering the levels of heparin in the blood to promote the clotting thus reducing excess bleeding. It can also be used in the treatment of other medical conditions.
Conditions that Protamine Sulfate can be used for:
- Excessive bleeding episodes
Protamine Sulfate Dosage
Protamine Sulfate must be administered in controlled and regulated manner. The physician must subject an accurate dosage for the drug to be effective. Protamine Sulfate should be administered as directed by the manufacturer. It should only be administered as an injection intravenously and not in any other way. The right dosage might also be determined by the severity of the condition.
Usual adult dose for:
- Protamine Sulfate must be given by a slow intravenous injection of 10 mg/mL over 10-minutes period. The maximum dosage that must be administered should be 50 mg.
Usual pediatric dose:
- The safety and the efficacy of Protamine Sulfate medicine to the pediatric patient are yet to be established and thus it should not be prescribed to them.
Protamine Sulfate Side Effects
Like other drugs, Protamine Sulfate is associated with different side effects although some of the patients may not be affected by majority of these effects. Protamine Sulfate side effects can be less severe if the drugis usedas per the provided prescription or manufacturer direction. The side effects may be categorized as common while others are severe side effects. You should check with your doctor if the any of the side effect persists for long.
Common side effects are:
- Mild diarrhea
The severe side effects are:
- Severe diarrhea
- Mouth swelling
- Tingling of the skin Burning
- Bright red blood in your stool
- Allergic reactions
- Unusual tiredness
Protamine Sulfate Interactions
Protamine Sulfate does interact with a few drugs and substances. Always get to know the drugs that can possibility interact with this drug before taking it to avoid severe side effects. Some of the Protamine Sulfate interacting drugs are known for causing severe side effects especially if they are not managed on time. It is important to have adequate information about them.
These are the drugs that can interact with Protamine Sulfate: