Promacta, generic name eltrombopag, belongs to a group of drugs known as Platelet-stimulating agents. Promacta is a man-made form of a protein that functions by increasing the production of the platelets in the body of the patient. Promacta can lower the risk of bleeding in patients by increasing the platelets in the blood.
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Promacta is used by medical practitioners to treat low platelets in patients that have a certain blood disorder known as Chronic immune thrombocytopenic purpura or who have chronic hepatitis C. Promacta may also be used by physicians to treat patients that have a certain blood disorder called aplastic anemia. The platelets in the body are a type of blood cell needed to form blood clots and prevent bleeding. Promacta functions by decreasing the risk of a patient bleeding by increasing the number platelets in the body. Promacta acts like a particular natural substance that is found in the body that causes the production of platelets.
- Hepatitis C
- Thrombocytopenic Purpura
- Aplastic Anemia
For administration of Promacta, use the lowest dose to achieve and maintain a platelet count that is equal or greater to 50*10-9/L as necessary to be able to reduce the risk of the patient bleeding. The dose adjustments of this medication are based on the platelet count response. Patients are advised not to use Promacta to normalize platelet count. In trials, the platelet counts have been found out to increase within 1-2 weeks after discontinuing the use of Promacta.
- Patients should initiate Promacta at a dose of 50 mg once daily, except in patients who are of east Asian origin, or rather who have mild to severe hepatic impairment.
Promacta Side Effects
Patients should note that not all the side effects associated with Promacta have been reported. Therefore, they should seek medical advice regarding the use of this medication before prescription. While using Promacta, some patients may experience some unwanted effects from the medication although some of the side effects may not necessarily need medications. Adverse or persistent effects from the drug may need immediate medical attention. Patients should not start, stop or change this medication without the approval of a physician. Some of the side effects are listed below.
- Pale skin
- Lose of voice
- Runny nose
- Rapid weight gain
- Yellow skin
- Sore throat
- Bladder pain
- Blurred or decreased vision
- Burning sensation
Interactions with Promacta can cause this medication to change the way it functions in the body of a patient. Interactions with this medication can lead to very severe side effects. Therefore, patients should inform their doctor of all the medications that they may be using before they begin medicating on Promacta to assist in prescription. Some of the known interactions of this medication are listed below.