Brand Name(s): Condylox,Condyline
Drug Class: Keratolytic
Treats: Externanital Warts,Vesicant agent,Antiviral agent,Antitumour agent,Antirheumatic agent ,purgative agent.
Podofilox is a Non alkaloid toxin mainly obtained from the rhizomes and roots of Podophyllum type. Podofilox is mainly applied on a human being skin to treat external genital Warts caused by certain Human Papillomaviruses (HPVs) and other Warts.
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Podofilox is highly effective, and its usage comprises application of the medication in weeks to the affected areas by a medical expert. Etoposide is a derivative of Podofilox that activates DNA breakdown by interdiction of Topoisomerase II, and the drug's optimum activity is at the late S and early G2 phases of the cell cycle. The drug's derivative display obligatory activities to the stimulant, Topoisomerase II during the early G2 and late S Stages. These derivatives demonstrate an anti-cancer activity useful in various chemotherapies like genital tumours and lung cancer.
Patients should not use this product without instructions from a medical expert. It is through consultation that the patient will understand the proper method of application as well as identifying the specific Warts that require cure. Podofilox should be applied in the morning and evening for 3 consecutive days. The patient should then withhold usage for 4 consecutive days, and the one-week treatment cycle may be repeated for a maximum of 4 times to make sure that there are no visible Wart tissues.Podofilox Topical Solution should be applied with an applicator provided together with the drug. The treatment should be
- Less than 10cm Square of wart tissue and should not be more than 0.5 ml of the solution every day.
Podofilox Side Effects
When medications react with food substances and other prescribed drugs, they sometimes cause undesirable effects in the body. These effects may rage from mild to serious and it is therefore important for the patient to provide detailed information on diet programs they are undertaking as well as other medication they are using for other conditions. Mild effects may not necessarily need a doctor's attention but in case a patient has severe ones, it is required of him/her to consult a medical professional. Toxic doses of Podofilox cause intense enteritis and severe CNS depression which may result to death. Other side effects that may occur following the drug's usage include
- Small sores
- Peeling skin
Administration of drugs can sometimes be followed by a serious interaction due to the presence of other medications and food substances in the body. Alcohol consumption during therapy should be avoided because it can lead to a serious drug interaction thus putting the life of the patient at a risk. Excessive topical usage of Podofilox may lead to fatal or near fatal reactions especially when used on mucous membranes. Podofilox interaction with other drugs has not yet been recorded but there are certain medical conditions that may interact with this drug such as
- Poor circulation
- Diabetes mellitus
- Corticosteroid therapy
- Allergies to medicine
- Allergies to food
- Bleeding warts
- Unusual warts with hair growing