Brand Name(s): Rapivab
Drug Class: Neuraminidase inhibitors
Treats: Flu, influenza
Peramivir is approved by the FDA for use as a single IV dose in the treatment of acute uncomplicated influenza in adults. It should be noted that Peramivir should be administered within 2 days of the onset of influenza symptoms. Peramivir is the first neuraminidase inhibitor available in an intravenous formulation.
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Peramivir is used to treat acute uncomplicated influenza in adults who have been symptomatic for a period of no more than two days. For patients with an impaired renal function adjust the dosage to 200 mg and 100 mg. Efficacy is yet to be established in individuals with influenza B. Neuraminidase inhibitors prevent the release of virus from infected cells and reduce further infection. Its greatest benefit is seen with early initiation that is less than 48 hours after the onset of symptoms. Below you will find a list of Peramivir uses.
- Acute uncomplicated influenza
Peramivir dosage depends on the individual and the condition being treated. Peramivir is available as a 200 mg or 20 mL single vial that can be kept at room temperature. Once it is diluted, it can be refrigerated for a period of 24 hours. To make a standard 600 mg dosage, you will require three vials. Safety and effectiveness in pediatric patients is yet to be determined. In a trial that was conducted in Japan, 117 pediatric subjects with uncomplicated influenza were treated with a singular dose. Below you will find a typical Peramivir dosage.
- The recommended dose is a single 600 mg dose which is administered via intravenous infusion for 15 to 30 minutes.
Peramivir Side Effects
Peramivir is in most cases well tolerated but can cause many different side effects. It is important to tell a health-care professional concerning any side effects so that you can be monitored. If you suffer side reactions please contact your doctor as soon as possible. Depending on the severity of the reaction, your doctor may adjust your dose or even discontinue the administration of the medicine. Below you will find a list of Peramivir side effects. Note that not all possible Peramivir side effects are listed.
- Sore throat
- Nasal congestion
- Sore throat
- Stevens-Johnson syndrome
Like any drug, Peramivir may interact with other drugs and substances. Tell your doctor about any drugs you are using, including over the counter drugs and supplements. Drug interactions may change the way your medication works or increase the risk or severity of your side effects. Below you will find a list of potential Peramivir drug interactions. Note that not all possible Peramivir interactions are listed here.
- Vitamin C