Lipopeptide antibiotics are used in the fight of bacteria in the body. It is used in the fight of infection brought by bacteria. Gram-positive is one of the things that lipopeptide treats that is an organism that occurs naturally in the soil saprotroph. These classes of drugs have a unique mechanism of action that is used to protect individuals against the infection. Most of the antibiotics deal with having pathogens being inactivated or killed; this is not the case with lipopeptide antibiotic. This is due to the undesirable reaction of the host bacteria, inability of having the culture of the pathogen, and reverse to virulence.
Lipopeptide Antibiotic Drugs
Drugs under this class include:
Lipopeptide Antibiotic Uses
Lipopeptide antibiotic is able to get rid even the most stubborn bacteria. It is an antibiotic that can be used to treat Gram-positive one of the most stubborn bacteria and other multiple antibiotic resistant as well as susceptible strains. It is also approved for the treatment of skin complication and infections that are connected to some of the tough pathogens.
It is the unique structure of lipopeptide antibiotics that consist of 13 members of amino acids that makes this drug able to deal with these pathogens. Lipopeptide is put to the tail of the bacteria cell membrane causing the membrane to depolarize and there to be ion efflux of potassium. This is followed by there being an arrest of protein, DNA and RNA synthesis that results in the death of the bacterial cell. The effect of the bactericidal is rapid and has greater than 99.9% of both MRSA and MSSA bacteria dying in duration of less than one hour. This rapid death of the cell does not turn to rapid bacterial lysis of the cell. Daptomycin also remains bacterial such that 99.9% are destroyed within the first 24 hours. This is against stationary stage, where culture of MSSA and MRSA offer a high density in simulated.
Lipopeptide Antibiotic Side Effects
Lipopeptide antibiotics may cause side effects. Though they should go away after some time;
- Stomach pain
- Falling or staying asleep
- Unusual weight gain
- Increased urge to urinate
- Redness, pain, swelling at the injection site
There are also some side effects that are serious;
- Blisters or peeling of skin
- Chest pain
- Shortness of the breath
- Worsening fever
- Fast heartbeat
- Numbness of the limbs
- Pale skin
Lipopeptide antibiotic may cause other side effect, in case you have any unusual problem while using this medication you should call a doctor.
Lipopeptide Antibiotic Interactions
It is important before taking this medication to inform the doctor if there are other medications that you are taking. There are some chemicals that react with this drug in a negative manner. To avoid this ensure that you have consulted the doctor. It is also important to finish the medication that you have been giving so that it can be effective.