Leukotriene is a group of active compounds obtained from arachidonic acid which function as regulators of allergic and inflammatory reactions. The release of leukotrienes causes airway constrictions, an increase in mucus production, swelling and inflammation in the lungs. This is what usually presents itself as wheezing. Leukotriene Receptor Antagonists (LTRAs) are a group of oral medication which are non-steroidal and come in the form of tablets. They stop the effect of cysteinyl leukotrienes which trigger chemical mediators of asthma. LTRAs are the best known drugs to manage asthma treatment and prevent acute asthma attacks.
Leukotriene Receptor Antagonists Drugs
Below are listed some of the common drugs in the Leukotriene Receptor Antagonists class.
Leukotriene Receptor Antagonists Uses
When used for a short period of time, Leukotriene receptor antagonists moderate the symptoms of asthma. In addition, LTRAs treat allergic rhinitis, which occurs when the immune system overreacts and retaliates to a harmless protein in the system. This results in the production of inflammatory chemicals which combine with other cells and lead to inflammation. Below you will find a list of uses for LTRAs.
- Allergic rhinitis
Leukotriene Receptor Antagonists Side Effects
Because of the way they interact with the body, Leukotriene Receptor Antagonists can have a variety of side effects. Some of the most common side effects are listed below.
- Mild stomach pains
- Allergic reactions
- Difficulty in breathing
- Suicidal thinking
Leukotriene Receptor Antagonists Interactions
Consult with your doctor about any other medications you are taking. Anticoagulants like warfarin should be used with caution because they increase the risk of bleeding when combined with some LTRAs. Pregnant and breastfeeding mothers should consult a doctor first. Let your doctor know if you have a history of depression or suicidal thoughts.