Ketoprofen is an oral medication belonging to a class of drugs known as nonsteroidal anti-inflammatory drugs or NSAIDs. It is used to relieve mild to moderate pain, swelling, tenderness, and stiffness that may be caused by conditions like osteoarthritis and rheumatoid arthritis. It works by blocking enzymes that help in the synthesis of prostaglandins.
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Ketoprofen reduces the chemicals known as cyclo-oxygenase or COX enzymes that help in making other chemicals known as prostaglandins. When COX enzymes are reduced, it means fewer prostaglandins are produced at the site of damage or injury, which further eases inflammation and pain. This drug may be combined with another medication known as omeprazole to prevent stomach irritation, which is a common side effect.
Ketoprofen treats pain associated with different diseases and health conditions such as:
- sprains and strains
- menstrual cramps
- and post-operative pain.
It may also treat pain induced by
- muscle aches
- the common cold
Ketoprofen comes in form of ordinary capsules as well as long-acting capsules taken orally. The dose administered may depend on the condition or disease that is being treated.
- Rheumatoid arthritis- 75 mg of ketoprofen taken orally three times every day or 50 mg taken four times in a day.
- Osteoarthritis Pain- 70 mg of the drug is taken three times in a day or 50 mg taken four times in a day. For extended-release, 200 mg of this drug is taken one time a day.
- Acute gout- 100 mg of ketoprofen is taken orally once and then 50 mg in every 6 hours until the attack subsides. This may take about 2 to 3 days.
- Dysmenorrhea- 20 to 50 mg of the drug taken orally in every 6 to 8 hours to relief pain.
Ketoprofen Side Effects
Many medicines will cause unwanted side effects, but not everyone may experience them. Some side effects may improve as the body adjusts to the medication, but you should talk to a doctor if these effects become troublesome or persists:
- Sores in mouth
- Ringing in ears
- Difficult in staying or falling asleep
Ketoprofen may induce serious side effects in a patient. You may want to talk to a doctor if you experience unusual effects while taking this medication.
- Change in vision
- Lack of energy
- Back pain
- Bloody or discolored urine
- Fast heartbeat
- Yellowing of eyes or skin
- Difficulty in breathing or swallowing
- Swelling of eyes, lower legs, hands, tongue, ankles, arms, lips or throat
Ketoprofen may interact with other drugs. You should ask your doctor if this medication interacts with other drugs you might be taking. Ketoprofen may interact with drugs listed below, but this may not be a complete list:
This drug may reduce excretion of lithium in the body by the kidney, which may elevate the levels of this substance thus causing toxicity. The drug may also reduce effects of blood pressure medications. Patients taking blood thinners may want to avoid ketoprofen because it also thins blood and may cause excessive thinning of blood leading to bleeding.