Generic Name(s): hydralazine/hydrochlorothiazide/reserpine
Drug Class: thiazide diuretics
Treats: High blood pressure, edema
Hydrap-Es is a combination drug (hydralazine/hydrochlorothiazide/reserpine) that is used to lower blood pressure and decrease edema. Hydrap-Es may also be used to treat other conditions as directed by the doctor. Note that Hydrap-Es is only available through a doctor"s or physician"s prescription.
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The three components of Hydrap-Es work differently to lower blood pressure and treat edema. Hydralazine lowers blood pressure by relaxing blood vessels thereby making it easier for the heart to pump blood. Hydralazine belongs to a class of drugs known as vasodilators.
The hydrochlorothiazide in Hydrap-Es helps lower the patient"s blood pressure and reduce edema by increasing the amount of salt and water lost through the urine. Hydrochlorothiazide is a thiazide diuretic.
Reserpine, the other part of Hydrap-Es works by reducing the levels of a certain chemical in the blood. This in turn allows the blood vessels to relax and the heart to beat more easily and slowly. Hydrap-Es is typically indicated for:
- High blood pressure
The dosage for Hydrap-Es is determined by the doctor. The doctor may base an individual dose using on factors such as the patient"s weight, age, medical history and response to treatment. The amount of Hydrap-Es to be used is dependent on the strength of the drug. To help increase its effectiveness, avoid missing any doses. Also, take doses at an interval of 12 hours; in the morning and at night unless otherwise directed by the doctor. Below is a typical Hydrap-Es dosage:
- Initial dose: 1 tablet orally once every 24 hours
- Maintenance dose: 1 to 2 tablets every 24 hours in 1 to 2 divided doses
A missed dose should be taken as soon as possible. If it is about time for the second dose, the missed dose should be skipped and normal dosage returned to.
Hydrap-Es Side Effects
Hydrap-Es may cause varying side effects as is the case with any other drug. However, some patients may experience the side effects while others may not, mainly due the difference in the body"s ability to tolerate the effects of the drug. While common side effects may disappear on their own severe side effects may not and a doctor"s advice should be sought. Note that not all possible Hydrap-Es side effects are listed here.
Common Side Effects:
- Loss of appetite
- Mild pain in the eyes
- Upper stomach pain
Consult your doctor if you experience these severe side effects:
- Tightness in the chest
- Irregular of fast heartbeat
- Bloody stool
Hydrap-Es may interact with certain substances and drugs. Therefore, seeks your doctor"s opinion before combining Hydrap-Es with other drugs and substances. At the same time, avoid starting, stopping or changing the use of any medication while taking Hydrap-Es without informing your doctor. To make the monitoring of possible Hydrap-Es drug and substance interactions easier, share a list of all drugs, herbal supplements and minerals that you may be taking with your doctor. Note that Hydrap-Es may interact with other drugs and substances not listed here.
Hydrap-Es drugs and substance interactions
- Mag-Ox 400