Thrombocythemia is a rare disorder in which the body generates too many blood platelets. Platelets are parts of the blood that help in blood clotting. Thrombocythemia is more prevalent in people aged 50 and above although it can affect young people as well. It is slightly more frequent in women. Thrombocythemia is categorized under a class of conditions called myeloproliferative disorder.
|Drug name||Generic Name||Coupon|
|Agrylin||Anagrelide hydrochloride||Agrylin coupon|
|Intron A||Interferon alfa-2b||Intron A coupon|
|Pegylated interferon alpha 2a|
|Pegasys||Peginterferon alfa-2a||Pegasys coupon|
The first sign of Thrombocythemia is the development of a blood clot (thrombus). The clots can develop anywhere in the body. The signs and symptoms vary depending on where the clot forms. They include:
The less frequent symptoms of Thrombocythemia include:
If the clots occur in the brain, the patient may encounter the following symptoms:
The exact cause of Thrombocythemia is not known. However, research has it that approximately 80% of the people with Thrombocythemia have an acquired gene mutation that has a role in the development of the disease. The gene mutation may involve the gene mutations listed below:
A high count of platelets may also be caused by an underlying condition such as an infection or iron deficiency. Such a condition is known as reactive or secondary Thrombocythemia. Patients suffering from secondary Thrombocythemia have a lower risk of clots and bleeding.
If the patient has a blood count of 450,000 platelets or more, the doctor will carry out tests to establish an underlying condition. The tests are conducted to confirm a diagnosis of Thrombocythemia. The tests include:
The method used to treat Thrombocythemia primarily depends on the patient’s risk of blood clotting or bleeding episodes. In the event that the patient is younger than 60 and shows no signs or symptoms, the doctor may recommend periodic medical checkups. However, he or she may prescribe medication if:
A medical procedure known as plateletpheresis may be carried out only in emergencies such as stroke or dangerous blood clotting. The procedure is meant to lower the patient's platelet count temporarily.
Back to all Health Conditions