Paget's disease is a chronic disorder that affects the bone's remodeling process and commonly known as Osteitis deformans. Paget's disease may not show symptoms in its early stages, but it can be identified with an X-ray. The bones tend to fracture and break easily, and gradually get replaced with soft, porous bones. Paget's disease usually affects bones of the pelvis, skull, legs, spine and collar bone.
Whether it is monostotic (affecting one area) or polyostotic (affecting different parts of the skeleton), Paget's disease symptoms might be absent during its early stage. The most common symptom of Paget's disease is bone pain, but other mild and severe symptoms follow. The following are some of the common symptoms;
Since these are not the only symptoms associated with Paget's disease, it is recommended you inform your doctor in case of any other abnormal sign.
According to scientific researches, there is no specific cause of Paget's disease, but some people are at a higher risk of getting the disorder than others. The disease is said to run in families, with more than 30% of patients inheriting it from the family lineage. Sequestosome 1 gene on a chromosome is just an example of the gene associated with Paget's disease. To those with inherited genetics, viral infections increase the chances of them developing Paget's disease. Although Paget's disease affects people from every corner across the globe, it is especially common in Europe, New Zealand, and Australia. This implies that those in these areas are at an elevated risk of being affected by this chronic disorder. Below you will find some of the causes of Paget's disease.
Apart from depending on the signs and symptoms to determine the presence of Paget's disease in the body, a doctor may consider other techniques. In most cases, Paget's disease is diagnosed based on the appearances and images given after an X-ray. Using imaging tests like CT scan, MRI scan, and a bone scan, a medical practitioner can analyze the possibility of having Paget's disease. A blood test also known as serum alkaline phosphatase test can show the results after a Paget's disease treatment hence monitoring the patient's progress. Doctors, however, heavily depend on the bone scans since they show the entire skeleton and level of infection by the Paget's disease.
Doctors may not prescribe any medication to a Paget's disease victim until there are visible signs and symptoms, or after blood tests have shown its presence. There is no specific treatment of this chronic disorder, but some medications will help relieve pain and contain its symptoms. When the condition has caused adverse negative effects like bone deformities and breaks, then surgeries might be paramount to correct the condition. Some doctors will recommend the use of specialized footwear and heel lifts to support deformed bones and joints. Medication is also applicable alongside exercises and diet for Paget's disease, but with the advice of a medical practitioner. During medication, injectable calcitonin or bisphosphonates can be prescribed.
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