Generic Name(s): Diphenhydramine hydrochloride and lidocaine
Drug Class: analgesic
Treats: oral mucositis
First-Bxn is used to treat pain and protect ulcerations that occur as a result of cancer treatment. The mouthwash is sold under a number of other brand names and is often known as Magic Mouthwash. It is a frequent adjunct to cancer treatment as a method of alleviating oral mucositis, or the breakdown of tissues in the lining of the mouth in response to chemotherapy drugs.
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First-Bxn Mouthwash Uses
First-Bxn is used to treat oral mucositis, a painful breakdown of the lining of the mouth that comes about as a result of chemotherapy. The condition is a common side effect in the first several weeks of cancer treatment. It generally begins five to ten days into treatment, and persists for up to two weeks, resulting in painful ulcers in the tissues inside the mouth.
First-Bxn numbs the area to help alleviate pain while the condition persists. Various components of the mouthwash numb pain, promote healing, and prevent the growth of fungus and bacteria within the compromised tissues.
- Oral Mucositis
First-Bxn Mouthwash Dosage
While the different types of Magic Mouthwash comes in a variety of strengths and formulations, First-Bxn contains 200 mg of diphenhydramine hydrochloride, 1.6 g of lidocaine hydrochloride and 1.6 g of nystatin. The dosage depends upon the formulation that is prescribed, as well as the age of the patient.
- Adults typically take 15mL into the mouth and swish for 30 seconds, repeating every two to three hours.
- The formulation may also be prescribed for doses every four, six or eight hours.
- A safe dosage has not been firmly established for children. When using a 2% viscous solution of lidocaine, the maximum recommended dosage is 3 mg per kg of body weight, with at least two hours between doses.
First-Bxn Mouthwash Side Effects
When using First-Bxn, some patients may experience side effects, both mild and severe. This list is not exhaustive, but symptoms while using this product may include:
- sensitivity to light
- burning sensation in the mouth
- bad taste in the mouth
- abdominal pain
- dry mouth
This drug should be avoided during pregnancy and while breastfeeding since it can be transmitted to the infant through the placenta and breast milk.
First-Bxn Mouthwash Interactions
Some drugs may cause adverse effects when taken together. This drug has very few drug interactions, but they are considerably risky. First-BXN may increase the efficacy of anticoagulants like warfarin, leading to an excess thinning of the blood. In addition, it may decrease the efficacy of oral contraceptives, leading to unplanned pregnancy and possible transmission of the drug to the fetus. The drug also interacts unfavorably with antacids, dairy products and food, each of which may decrease the absorption rate of the active ingredients. Be sure to provide of all medications you are taking to your doctor.
- Oral Contraceptives