Brand Name(s): Nexium
Drug Class: Proton Pump Inhibitor
Treats: Duodenal Ulcers, GERD, Erosive Esophagitis, Dyspepsia, Zollinger-Ellison Syndrome
Esomeprazole strontium is a drug used in the treatment of conditions caused by the excessive production of stomach acid. Such conditions include GERD, duodenal ulceration, erosive esophagitis and Zollinger-Ellison syndrome. The drug belongs to a class of drugs known as proton pump inhibitors, meaning the drug will inhibit the release of acid-producing chemicals from pumps along the stomach wall.
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Esomeprazole Strontium Uses
Esomeprazole strontium is used in a variety of conditions, all of which have one central feature in common, the excessive production of stomach acid. As a result, the drug is used in the treatment of gastroesophageal reflux disease, Zollinger-Ellison syndrome, erosive esophagitis and duodenal and gastric ulceration. Even though esomeprazole strontium affects the symptoms of heartburn, it is not recommended for the treatment of heartburn. As a proton-pump inhibitor (PPI), the drug is recommended only in conditions where there is severe damage resulting from excessive acid production. Below you will find the uses of esomeprazole strontium.
- Duodenal ulcers
- Erosive esophagitis
- Zollinger-Ellison syndrome
Esomeprazole Strontium Dosage
Readers must take note that the doses listed below do not reflect every clinical circumstance. The dose chosen by the physician depends on additional existing factors such as age, pre-existing disease, and co-medication. However, the doses listed below reflect the typical doses in patients all else being equal.
- Zollinger-Ellison Syndrome: 40 mg orally twice daily
- Duodenal Ulcers: Initial IV infusion of 80 mg over half an hour; switching to maintenance dose of 8 mg/hr for 71.5 hours
- Prophylaxis of Gastric Ulceration: Initial IV infusion of 80 mg over half an hour; switching to a maintenance dose of 8 mg/hr for 71.5 hours
- Gastric Ulcer Adult Dose: 20mg or 40mg once daily for a maximum of six months
- Erosive Esophagitis: 20mg or 40mg once daily for a maximum of two months
- Gastroesophageal Reflux Disease: 20 mg once daily for one month
Esomeprazole Strontium Side Effects
Esomeprazole strontium generally has a well-tolerated side effect profile. However, with all drugs come risks, some of which are listed below. The most common side effects tend to be GI related, and may subside when given enough time. If the side effects you experience become too severe, you should stop the medication at once and consult your local healthcare provider. Common side effects include the following. Note that not all possible side effects are listed.
- Reduced appetite
- Abdominal pain
Consult your doctor should you experience any of the following symptoms:
- Allergic reaction
- Dry mouth
- Trouble swallowing
- Vomiting blood
- Severe abdominal pain
- Chest pain
- Extreme fatigue
Esomeprazole Strontium Interactions
Esomeprazole strontium has numerous clinically significant drug interactions, the most important of which are listed below. One of the reasons for this is because the drug affects the levels of certain enzymes in the liver, enzymes that are responsible for the rate of metabolism of other drugs. You should also inform your healthcare provider of any herbal remedies or supplements you are taking, as these can interact with medicines as well. Below you will find a list of drugs that may interact with esomeprazole strontium. Note that not all possible interactions are listed.