Brand Name(s): Halaven
Drug Class: Microtubule dynamics inhibitors
Treats: Advanced breast cancer
Eribulin is an anti-cancer drug. Eribulin is a synthetic derivative of the Japanese sponge, Halichondria Okadai. This drug comes in the form of an injection. It is an anticancer drug that belongs to the group of drugs known as microtubule dynamics inhibitors. Eribulin works by stopping the growth and spread of cancerous cells. It is a prescription only drug that comes only with a prescription from the doctor.
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Eribulin use is indicated for the treatment of metastatic breast cancer. In fact, Eribulin is prescription medicine specifically used in cancer patients who have received at least 2 other types of treatments or anticancer medicines in the past. Doctors prescribe Eribulin use for the treatment of breast cancer in patients who have received at least 2 chemotherapy sessions for late stage cancer disease. Research is undergoing for Eribulin use in the treatment of other solid tumors including prostate cancer, lung cancer, sarcoma and others.
- Breast cancer
Eribulin dose is normally determined by the doctor and is based on a number of factors such as the patient's medical history, age, response to medication and others.
- The recommended Eribulin dose is 1.4 mg per meter squared administered intravenously. Eribulin is administered over a period of 2, 5 minutes on days 1 and 8 in a 21-day cycle.
- For patients with mild hepatic impairment, the recommended Eribulin dose is 1.1 mg/meter squared while patients with moderate hepatic impairment take a recommended dose of 0.7 mg/meter squared. There are some provisions for the Eribulin dose modification. This modification is individualized and will be determined by the doctor.
Eribulin Side Effects
The use of Eribulin medicine in the treatment of breast cancer can result in a number of Eribulin side effects. Some of the symptoms are mild and will go away with time. The doctor can be informed if they do not go away with time or if there are serious side effects or an allergic reaction to the medication. Below is a list of common Eribulin side effects:
- Hair loss
- Joint pain
- Back and none pain
- Loss of appetite
- Nausea and constipation
It is important to inform the doctor about all the drugs, medicines and other products a patient may be using, such as multivitamins and diet or nutrition products. The reason is that there is a possibility of drug interactions with Eribulin. Some drugs that patients take may interact adversely with Eribulin, rendering it ineffective or resulting in serious or adverse reactions. A list of drugs that may interact with Eribulin are listed below: