Brand Name(s): Adriamycin, Rubex
Drug Class: Anthracyclines
Treats: Cancer, Hodgkin's disease, leukemia, lymphoma
Doxorubicin, an an anti-cancer drug, is indicated for treating many kinds of cancers such as breast cancer, leukemia, bone cancer, brain, cancer, and lung cancer. It is used in combination with some other cancer medications and offers antineoplastic or cytotoxic effects. This antitumor antibiotic works by stopping or altering the cell division of cancer cells through damage to the RNA and DNA that is critical in cell division.
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Doxorubicin treats different types of cancer, which include leukemia, bladder, breast, liver, lung, head and neck, as well as lymphomas. It also is administered to treat neuroblastoma, multiple myeloma, mesothelioma, stomach, prostate, testis, ovary, thyroid, uterus, and pancreas cancer. Patients with Hodgkin's lymphoma that begins in immune system cells may also be administered with this drug to help fight the cancer. Leukemia is a cancer of white blood cells, and patients who suffer from this disorder can be given this medication as part of the cancer therapy. Neuroblastoma is a cancer that starts in nerve cells and is mainly seen in children. Below you will find the uses of Doxorubicin.
Dosage of doxorubicin depends on the individual and the condition being treated. You should always use medication precisely as your doctor prescribes it. Doxorubicin is an IV infusion and will be administered and monitored by a healthcare professional. The length of treatment depends on the kind of other drugs you take and how the body responds. The period also depended on the cancer type you are suffering from. It may be used alone or in combination with other cancer medications.
- 40 to 60 mg per m2 administered intravenously in every 21 to 28 days
Doxorubicin Side Effects
Like any drug, doxorubicin may cause side effects. If you experience severe or persistent side effects, you should contact your doctor. Below you will find a list of side effects associated with doxorubicin. Note that not all possible side effects.
Contact your doctor immediately if you experience the following:
- Stomach pain
- Weight gain
- Increased thirst
- Loss of weight with reduced appetite
- Sores in throat and mouth
- Hair loss
- Eye pain
- Irritated watery or itchy and red eyes
- Red color of urine after a day or two
- Tingling burning or pain in hands and feet
- Toenails or fingernails separating from nail bed
Find medical attention immediately if you experience the following:
- Skin rash
- Difficulty breathing or swallowing
Doxorubicin could interact with other drugs. Patients should tell their doctor if they are under prescriptions of other medications whether over-the-counter or prescription drugs. The below list does not contain all possible drugs that could interact with Doxorubicin. The following drugs are likely to cause serious interactions with Doxorubicin. Note that not all possible interactions are listed.