Tafinlar, also referred to as dabrafenib, is a medication for cancer which interferes with the growth mechanism, as well as the spread of cancer cells in the body. It is used in the treatment of a particular type of metastatic (skin cancer that has spread to other parts of the body).
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Tafinlar is specifically recommended for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation. Tafinlar may also result in new cancers, including cutaneous squamous cell carcinoma (cuSCC) that is known to spread to other parts of the body. Make sure you consult with your healthcare provider about your risk of developing skin cancers.
Tafinlar is considered an inhibitor of some mutated forms of BRAF kinases. Some mutations found in the BRAF gene, including those that result in BRAF V600E, can lead to activated BRAF kinases that may stimulate tumour cell growth
- Metastatic melanoma with BRAF V600E mutation
- Cutaneous squamous cell carcinoma
- Skin cancers
Tafinlar dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Follow your medical professional"s directions for best results.
Tafinlar is administered in form of a capsule meant for oral administration.
- The recommended dose is 150 mg to be taken twice daily, at intervals of approximately 12 hours until the disease progression or unacceptable toxicity occurs.
However, you can take either at least 1 hour before or at least 2 hours after a meal. In case you miss a single dose, you can take it 6 hours prior to the next dose.
Dabrafenib Side Effects
It is very likely that some side effects of Tinactin may fail to be reported. These effects can be reported to the FDA. Make sure you consult your doctor in case you experience any of the following side effects:
- Stomach pain
- Blurred vision
- Dry mouth
- Dry skin
- Increased hunger
- Increased thirst
- Increased urination
- Skin blisters
- Skin rash
- Troubled breathing
- Weight loss
- Unusual tiredness
- Blurred vision
- Eye pain
- Darkened urine
- Fast heartbeat
- Loss of appetite
- Muscle aches
- Muscle pain or stiffness
- Pain in the joints
- Sore throat
- Stuffy or runny nose
In case you are taking Tinactin under the directions of the doctor, your doctor may already be aware of any possible interactions and may be monitoring you for them. Drug interactions may change the nature in which your medication work or increase your risk for serious side effects.