Zontivity is a thrombin receptor or protease-activated receptor antagonist. It is an anti-platelet drug, a treatment for coronary artery diseas,caused acute coronary syndrome chest pain. It inhibits platelet aggregation that is thrombin-related. Zontivity restores the blood flow to the heart in those who have experienced heart attack or have blockages in their arteries to the legs. It is designed to lessen the tendency of platelets to clump or stick together to become a blood clot. Zontivity works differently from other anti-platelet medications like aspirin, and it does not affect coagulation parameters, bleeding time and ADP-mediated platelet aggregation.