Trimethoprim is used in the treatment and prevention of urinary tract infections. It works as a bacteriostatic antibiotic, meaning that it does not kill bacteria but, instead, slows down the rate of reproduction. This means the body can use its internal defense mechanisms to eliminate the causative organism. The drug is taken orally and should, ideally, be administered on an empty stomach 1 to 2 hours before food. Trimethoprim is known to reduce platelet levels as a consequence of disrupting the synthesis of folic acid.