Tobramycin is a drug that belongs to the aminoglycoside antibiotics drug class. Tobramycin is derived from the bacterial species known as Streptomyces tenebrarius. Tobramycin is most effective against the gram negative bacteria like Pseudomonas. Therefore, Tobramycin can be used to treat various serious bacterial infections like eye infections, urinary tract infections, and pseudomonas infections. Tobramycin is able to treat these diseases by inhibiting bacterial growth.
Tobramycin sulfate is soluble in water and an antibiotic of the aminoglycoside group. It is obtained from actinomycete Streptomyces tenebrarius. Tobramycin sulfate is supplied as a sterile dry powder and is used for reconstitution along with 30 ml of Sterile Water for Injection. Tobramycin is a clear and colorless solution for being administered parentally. Tobramycin is an aminoglycoside antibiotic.
Tobramycin Sulfate fights infections that are caused by bacteria. Tobramycin Sulfate Inhalation is inhaled into the lungs using a nebulizer. Tobramycin Sulfate Inhalation is used in the treatment of lung infections in patients with cystic fibrosis.
Tobramycin works by binding to a site on the bacterial 50S and 30S ribosome, thus preventing the formation of the 70S complex. mRNA cannot be changed into protein, and cell death ensues. Also, aminoglycosides bind to the hammerhead ribozyme, tRNA, the Rev Response Element transcriptional activation region in HIV, the ribozyme from hepatitis self-splicing introns and delta virus.