Sertraline is a drug used in the treatment of psychiatric disorders such as major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, and panic disorder. The drug belongs to the SSRI class of medicines, meaning that it makes serotonin more accessible to the brain.Sertraline is a drug used in the treatment of a variety of depressive states. For example, it can be used in the treatment of major depressive disorder, social anxiety disorder, panic disorder, and obsessive compulsive disorder. Sertraline belongs to the SSRI, or selective serotonin reuptake inhibitor, class of drugs. This means that the drug enhances the presence of the neurotransmitter serotonin in the synaptic space between nerves. Enhancing serotonin levels is thought to increase positive mood and emotions in these patients. Common side effects with Sertraline include drowsiness, dizziness, nausea, appetite changes, weight changes, insomnia, and lowered sex drive.