Quetiapine is a very popular psychotropic medication used to treat symptoms of schizophrenia, bipolar disorder, and major depressive disorder. Quetiapine works to minimize psychotic features of these disorders. Quetiapine requires a prescription and cannot be purchased over-the-counter. The most common brand name of Quetiapine is Seroquel. Quetiapine is taken orally in the form of a pill.