Crestor (rosuvastatin) is part of the HMG-CoA Reductase Inhibitor or statin drug family. The prescription drug is used to lower cholesterol and triglycerides in the blood by slowing the buildup of plaque in an individual's arteries. Lowering cholesterol will help to decrease the risk of stroke and heart attack. Crestor is a drug that is used to treat high cholesterol levels. Typically, Crestor use is combined with healthy lifestyle changes. These may include beginning an exercise regime or changing your typical diet. Crestor is a trade name for Rosuvastatin. The drug is used to lower the cholesterol level in the blood. It should only be prescribed after diet, exercise and lifestyle changes have failed to change the cholesterol levels. Crestor works as an enzyme inhibitor. It restricts the function of a particular HMG-CoA Reductase by attaching to it. Due to its negative interactions with other drugs, it should only be taken when prescribed by a medical doctor.