Buprenorphine is a drug used in the treatment of pain and opioid addiction. Its function is highly dependent on dose, as lower doses are used exclusively for moderate pain relief while higher doses are used in opioid addiction. Common side effects with buprenorphine include nausea, diarrhoea and headache.Buprenorphine HCl is a semisynthetic opioid derivative of thebaine. Buprenorphine belongs to a class of drugs called mixed narcotic agonist-antagonists.It is a partial agonist opioid receptor modulator that's used in the treatment of opioid addiction in higher dosages, to control moderate acute pain in non-opioid-tolerant individuals in lower dosages and to control moderate chronic pain in even smaller doses. Buprenorphine HCl is available in some formulations: Cizdol, Suboxone, Bunavail (available as buprenorphine and naloxone HCl or buprenorphine HCl alone); typically used for opioid addiction, Buprenex, Temgesic, Norspan, and Butrans. Buprenorphine is used in the treatment of addiction to narcotics. It helps prevent withdrawal symptoms caused by stopping other opiate-type narcotics. Buprenorphine is used as part of a complete treatment program for drug abuse (such as compliance monitoring, counseling, behavioral contract, lifestyle changes).