Aptivus (tipranavir) is an antiviral medication known as protease inhibitor. Aptivus helps prevent human immunodeficiency virus (HIV) cells from multiplying in your body. Aptivus is capable of inhibiting the viruses' replication that are quite resistant to other protease inhibitors. Aptivus is recommended for those patients who show resistance to other treatments. Resistance to Aptivus itself seems to require multiple mutations of the HIV virus.