Cisplatin is a chemotherapy drug belongs to a class of medication known as platinum-containing anticancer medicines. Cisplatin is used in the treatment of various cancer infections such as lung cancer, sarcomas, ovarian cancers and germ cell tumors. Cisplatin works by binding to and causing cross-link of DNA which triggers cell death in the body.
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Cisplatin is a short-term medication in the treatment of solid malignant growths in the body. Cisplatin can also be in the treatment of various cancers, including sarcomas, carcinomas, lymphomas, bladder cancer, and cervical cancer. Cisplatin is in a combination with other drugs such as bleomycin and vinblastine to treat testicular cancer. Some of the symptoms of these diseases include bloody urine, hematuria, and pain in affected parts, frequent urination, vaginal discharge, ulceration, diarrhea, and headache. Cisplatin is an antineoplastic agent. Cisplatin works by stopping cancer cells from growing and reproducing the effects brought about by such conditions.
- Malignant Growths
Cisplatin dose is dependent on the type of cancer one is suffering from. Most doctors will prescribe a different regimen to different patient with the same disease depending on the heath condition and other factors of the body that may stimulate side effects. Most recommended dosage for Cisplatin includes: Adult
- Testicular cancer: 20 mg/m2 daily for 5 days.
- Ovarian cancer: 75-100 mg/m2 once every 4 weeks
- Bladder cancer: 50-70 mg/m2 every 3 to 4 weeks
- Neuroblastoma: 60 to 100 mg/m2 once every 3 to 4 weeks.
- Lung cancer: 60 to 100 mg/m2 on day one every 21 days.
- Cervical cancer: 40 to 70 mg/m2 weekly.
Cisplatin Side Effects
Cisplatin just like most drugs can cause side effects in the body. Patients treated with Cisplatin report cases of an allergic reaction; a few may have side effects ranging from mild to severe. Seek medical attention in case you have the following common side effect of Cisplatin:
- loss of appetite
Severe side effect of Cisplatin includes:
- severe allergic reactions
- blood in the urine
- bloody stools
- chest pain
- decreased urine volume
- irregular heartbeat
- hearing problems
- joint pain
- loss of balance
Drug interaction to cisplatin affects its action in the body. Most drugs interact with cisplatin lowering its effectiveness. Discuss with your doctor all the medication you are using, those prescribed and over-the- counter. Also, report cases of allergic reactions suspected due to use of Cisplatin drug. Do not stop or start cisplatin dosage without advice from the healthcare provider.