Brand Name(s): Paraplatin
Drug Class: alkylating agents
Treats: cancers including ovarian and cervical
Carboplatin is a generic antineoplastic drug commonly used to treat ovarian and cervical cancers. It may also be used in the treatment of some pediatric cancers, but it is not FDA approved for these uses. It affects the way cancer cells grow and spread.
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Carboplatin works by interrupting development and growth of cancer cells. It is used specifically in the treatment of ovarian and cervical cancers, plus some pediatric cancers, including brain tumors and solid tumors. It can also be used in preparation for a bone marrow transplant. Carboplatin may not be appropriate for patients who suffer from severe bone marrow or bleeding disorders, kidney problems, or low electrolyte levels. It may also cause reactions in patients who have an allergy to platinum.
- Ovarian Cancer
- Cervical Cancer
- Bone Marrow Disorders
Dosage of Carboplatin depends on the individual and the condition being treated. You should always take medication precisely as your doctor prescribes it. It is important to remember to follow the diet described to you by your doctor while taking Carboplatin. Below you will find a typical dosage of Carboplatin.
Recurring Ovarian Cancer
- When combined with 600 mg of cyclophosphamide, the dose is 300 mg per square meter of skin surface area, repeated every four weeks for six cycles. Using the Calvert formula, carboplatin may be given alone in a dose ranging from 600 to 900 mg, which does not take skin surface area into account, but rather is determined based on blood serum measurements to prevent overdose.
- 200 mg per square meter of skin surface area administered on day one of each 21-day treatment cycle
Carboplatin Side Effects
Carboplatin, like any other drug, comes with its collection of side effects that vary with each individual who uses it.Some patients may experience side effects, both mild and severe while taking Carboplatin. This list is not exhaustive, but you should contact a doctor immediately if you experience severe side effects.
- pain at injection site pain in the back or side
- blood in urine or stool
- tarry stool
- skin reaction
- unexplained fatigue
- unexplained bruising or bleeding
As with all drugs, before taking Carboplatin, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. You should also let your doctor know if you are pregnant or breastfeeding, and if you have any allergies to drugs or foods.