Generic Name(s): Ergotamine/caffeine
Drug Class: Ergot Derivatives
Treats: Migraines, cluster headaches
Originally manufactured by Novartis and approved by the FDA back in 1948, Cafergot is a medication prescribed for the treatment of severe vascular headaches. Vascular headaches are cluster and migraine headaches. The active ingredients in Cafergot are ergotamine tartrate and caffeine. Ergotamine tartrate is an ergot alkaloid and these act as vasoconstrictors. Cafergot acts to constrict the widened blood vessels in the lining of the brain reducing the throbbing and pain associated with the headache. Cafergot should be avoided by those with kidney disease, high blood pressure, heart disease, circulatory issues, blood vessel disorders or liver disease. Cafergot is available as rectal suppositories, tablets, and sublingual forms.
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Cafergot is used for the treatment of moderate to severe vascular headaches known as migraine and cluster headaches. Cafergot is most effective when used at the first sign of the headache. After a delay, Cafergot is found to be less effective. Cafergot should not be used if pregnant as it can cause birth defects. It can also pass into mother"s breast milk which can harm the infant. Long term usage of Cafergot is not advised and can be addictive. After several weeks of ongoing usage, or with high dosages, Cafergot can cause a withdrawal reaction.
Below, you will find the primary uses for Cafergot:
Cafergot dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Do not take a larger dose or more frequent doses without approval from your doctor. Follow your medical professional"s directions carefully for best results.
- 2 mg taken initially in tablet or sublingual form, followed by an additional 2 mg every 30 minutes to a maximum dosage of 6 mg total
Cafergot Side Effects
Cafergot, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Cafergot, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
Below you will find a list of drugs and substances that interact with Cafergot. As with all drugs, before taking Cafergot, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. Do not let anyone else take your medication, and consult your physician before taking any new medication. Note that this list is not complete.
- Alsuma (sumatriptan)
- Agenerase (amprenavir)
- Amerge (naratriptan)
- Atripla (efavirenz, emtricitabine, tenofovir)
- Axert (almotriptan)
- Atapryl (selegiline)
- Azilect (rasagiline)
- Drisdelle (paroxetine)
- Carbex (selegiline)
- Cymbalta (duloxetine)
- DHE 45 (dihydroergotamine)
- Darpaz (hyoscyamine, methenamine, methylene blue, phenyl salicylate)