Cabazitaxel is used together with a steroid medicine such as prednisone to treat men with metastatic prostate cancer. Cabazitaxel belongs to a group of cancer-fighting medicines referred to as antineoplastics. Specifically, Cabazitaxel belongs to the group of antineoplastics called texanes. Cabazitaxel works by slowing or stopping the growth of cancer cells in your body.
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Cabazitaxel is approved for the treatment in combination with prednisone of patients with castrate resistant metastatic prostate cancer that was formerly treated with a docetaxel-containing medicine. Cabazitaxel is given intravenously, and there is no pill form. You will take a corticosteroid pill, prednisone while being treated with Cabazitaxel. Cabazitaxel is a microtubule inhibitor. Microtubules are essential to cell division, and texanes, such as Cabazitaxel, stabilize a particular type of protein in the microtubule
- Prostate cancer
Cabazitaxel doses depend on many factors, such as height, weight, general health and the type of condition you have. The following information provides an average dose, and your doctor will determine what best suits you individually.
- The recommended dose is Cabazitaxel 25mg/m2 administered every three weeks as a one-hour intravenous infusion in combination with prednisone 10 mg administered each day in the course of treatment.
- Cabazitaxel should not be administered to patients if the neutrophil counts are ?1,500 cells/mm3 or if they have a history of severe hypersensitivity to Cabazitaxel. Primary prophylaxis with granulocyte colony stimulating factor may be considered in patients with high-risk clinical ages.
- The safe use and efficacy of Cabazitaxel in children is yet to be determined.
Cabazitaxel Side Effects
Cabazitaxel may cause unwanted effects. The side effects may be reported to the FDA. It is essential that your doctor checks your progress while you are using Cabazitaxel. Blood tests may be deemed necessary to check for negative effects that include:
When you are using Cabazitaxel, it is important that your physician know if you are taking any of the medicines listed below. Using Cabazitaxel together with any of the following medicines is not recommended, but may be necessary in certain instances: