Brand Name(s): Velcade
Drug Class: Antineoplastic agents
Treats: Multiple Myeloma, Hepatic function impairment
Bortezomib, also known as Velcade, is an antineoplastic agent which is available for intravenous and subcutaneous use. Each use has 3.5 mg of the drug which acts as a sterile lyophilized powder. The drug is used to treat patients with multiple myeloma who have used other treatments. It is also used in treating patients with mantle cell lymphoma who have also used other types of medication. The drug works by killing cancer cells directly.
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Bortezomib is an injection that is used as a form of chemotherapy medication for cancer. By blocking certain proteins, Bortezomib can slow down the cancerous cells in the body so that its growth and spread are limited. In time, the cells are destroyed by the body.
Below you will find the different types of conditions that can be treated by using Bortezomib:
- Multiple myeloma
- Mantle cell lymphoma(non-Hodgkin's lymphoma)
Bortezomib dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Do not take a larger dose or more frequent doses without approval from your doctor. Follow your medical professional's directions carefully for best results.
Untreated Multiple Myeloma
Hepatic function impairment
- 0.7mg/m initial dose, with increased dosage over one week
Bortezomib Side Effects
Bortezomib, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Bortezomib, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
- Loss of appetite
- Mild stomach pains
- Trouble sleeping
- Change in the urine production
- Behavior changes
- Severe or persistent nausea
- Bloody or black stools
Below you will find a list of drugs and substances that interact with Bortezomib. As with all drugs, before taking this medication, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. Do not let anyone else take your medication, and consult your physician before taking any new medication. Note that this list is not complete.
- CYP3A4 Inducers
- St. John's Wort