Brand Name(s): Avastin
Drug Class: VEGF/VEGFR inhibitors
Treats: brain cancer, lung, kidney cancer, ovary cancer, cervix cancer, rectum cancer, colon cancer
Bevacizumab is used to treat cancers in a number of internal organs, and works by inhibiting the growth of cancer cells. Bevacizumab can encourage bleeding, and therefore should not be used within the month before a surgery. The growth of cancer cells comes from abnormal programming in their internal genetic material, which makes them multiply at a destructive rate. Bevacizumab helps to control the growth of these cells.
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Bevacizumab is used to treat individuals suffering from lung cancer, colon cancer, renal cancer, brain tumors, thyroid cancer, vitreomacular adhesion, and macular degeneration. The drug is a VEGF antibody that helps to prevent the growth and spread of cancer cells. Bevacizumab is typically used when the cancer has spread throughout the body. It may also be used in combination with other medications to remove certain nutrients from the body that cancer cells use to grow. Below you will find the different uses for Bevacizumab:
- Lung Cancer
- Colon Cancer
- Renal Cancer
- Thyroid Cancer
- Brain Tumors
- Vitreomacular Adhesion
- Macular Degeneration
Bevacizumab dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Do not take a larger dose or more frequent doses without approval from your doctor. Follow your medical professional's directions carefully for best results.
- Colorectal cancer: 5 to 10 mg per kg of body weight perweek
- lung cancer: 15 mg per kg of body weight every three weeksin combination with chemotherapy
- breast cancer :10 mg per kg of body weight every two weeks
- glioblastoma multiforme: 10 mg per kg of body weight every two weeks
- ovarian cancer:15 mg per kg of body weight every three weeks
- renal cell carcinoma:10 mg per kg of body weight every two weeks
pediatric dosage for solid tumors:
- 15 mg per kg of body weight every two weeks when used alone
- 5 to 10 mg per kg of body weight every two weeks when used with other drugs
Bevacizumab Side Effects
Bevacizumab, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Bevacizumab, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
- chest pain
- irregular heartbeat
- difficulty breathing
- cloudy urine
- decreased urination
- black stool
- weakness loss of appetite
- unusual fatigue
- bloody stools
- severe weakness or dizziness
- severe abdominal pain
- vomit that looks like ground coffee
- vision problems
- sudden headache
- difficulty speaking clearly
Below you will find a list of drugs and substances that interact with Bevacizumab. As with all drugs, before taking this medication, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. Do not let anyone else take your medication, and consult your physician before taking any new medication. Note that this list is not complete.