This class of medication can be referred to as the preventers. These preventers are applied in the maintenance treatment or in the reduction of airway inflammation. The combination is composed of inhaled corticosteroid + long-acting beta2 agonist drugs (eformoterol/budesonide, eformoterol/fluticasone and the salmeterol/fluticasone). The long-acting beta-agonists + inhaled corticosteroids have since been endorsed in the guidelines for the cure of chronic obstructive pulmonary disease. Their co-administration in a merged nebulizer or inhaler is meant to improve adherence to drug regimens and to facilitate efficacy. The two preparations presently available for this combination include the budesonide/formoterol and the fluticasone/salmeterol. Combination LABA and ICS considerably lower the mortality and morbidity rate in COPD when matched to the mono component steroid. Hostile events were never considerably different between treatments, though evidence achieved from researches show that inhaled corticosteroids are linked with increased risk of pneumonia. The assessment of BDF in bigger and long term trials is necessary when prescribing the use of this combination. Dose response information would give valid evidence on whether safety and efficacy outcomes are affected by diverse steroid loads.
Beta Agonist + Corticosteroid Combinations Drugs
The list of drugs in this class include:
Beta Agonist + Corticosteroid Combinations Uses
The beta agonist + corticosteroid combinations are applied in the treatment of asthma and COPD. The combination works by preventing lung inflammation and relaxation of the airways for sufficient airflow.
The conditions treated by this drug combination are those related to breathing problem among children. The COPD is considered a debilitating condition that is considerably characterized by the irreversible, progressive airflow limitation through the lungs.
Beta Agonist + Corticosteroid Combinations Side Effects
All types of medication contain side effects. But several persons do not feel them, or they are capable of dealing with them. It is, therefore, advisable that one asks his or her pharmacist about the exact side effects of any prescribed medication before taking it. One should also check the side effects of the information accompanying the medicine provided.
Some of the side effects experienced while using this combination include:
- Reluctant spontaneous muscle twisting-this majorly occurs in the small muscles of the lower eyelid
- Muscle cramps within the toes, hands, and foots
- Muscle cramps in the calves during the morning hours
- Hand tremor
- Irregular or increased heart palpitations
- Sore throat experienced with a deeper voice
- Dry throat
- Oral thrush within the past 90 days
- Skin bruises lacking a substantial blow to the skin site in question
Similarly, the side effects are most probably to be experienced when this combination of drugs is consumed as an injection or pill than when inhaled.
Beta Agonist + Corticosteroid Combinations Interactions
The drug combination is used for both long-term and short-term relief signs. The drug can also be used before an asthmatic person goes for exercise in order to minimize the breathing problems. Additional use of the drug with formoterol, salmeterol or eformoterol is necessary in order to prevent the shortness of breathing or coughing that might prevent you from doing exercises. Combining together the corticosteroid with the eformoterol and giving it once or twice on a daily basis will upgrade and improve hyperinflation and airway obstruction.