Generic Name(s): Pipecuronium bromide
Drug Class: Neuromuscular blocking agents
Treats: relaxant, anxiety, muscle tension
Arduan is used to adjunct general anesthesia to allow relaxation of skeletal muscles during surgery. Arduan is also used to relax the throat to allow insertion of a breathing tube before surgery in a process known as ET intubation. Arduan is recommended for procedures that last 90 minutes or more.
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Arduan is only used in a clinical setting and is administered by a qualified medical practitioner. Arduan works by inhibiting nerve transmissions in nerve muscles. This action leads to relaxation and paralysis. The paralysis is selective at the first few minutes and occurs consecutively in levator muscles of the eyelids, muscles of mastication, limb muscles, and abdominal muscles, muscles of the glottis and the intercostals muscles as well as the diaphragm. Arduan may also be used for other condition not listed in this medication guide as directed by the doctor. Arduan is used for the following.
- Allow relaxation of skeletal muscle during surgery
- Facilitate ET intubation
Arduan dosage is determined by the doctor. Arduan is administered as an intravenous injection through a vein or muscle. The doctor may base the dose on factors such as the patient's age, weight, sex and response to treatment may determine the dosage. The amount of Arduan to be administered depends on the strength of the medicine. Below you will find a typical Arduan dosage.
- Arduan Initial dose: 0.08 to 0.1 mg/kg. Maintenance dose during prolonged surgical procedures: 0.01 to 0.015 mg/kg 25 to 40 minutes later, then as frequently as every 12 to 15 minutes.
- Continuous infusion: Initiate with an intubating dose of 80 to 100 mcg/kg followed 20 to 40 minutes later with 0.8 to 1.2 mcg/kg/minute.
Arduan is used as needed and the doctor may advise on the next course of action in the event of a missed dose.
Arduan Side Effects
Just like any other drug, Arduan has some side effects. The acuteness of these side effects may differ depending on the person using the drug. Nonetheless, the doctor will closely monitor your breathing, heart function, oxygen level and other vital signs while Arduan is being administered. Below you will find some common side effects of Arduan. Note that not all possible side effects are listed.
Common Arduan Side Effects
- Loss of appetite
Severe Arduan Side Effects
- Inability to breath
- Irregular heartbeat
- Blood stains in stools
- Inability to urinate
Certain drugs and substances may interact with Arduan and delay or affect how the drug works. Mostly, it is only under a doctor's direction that Arduan is combined with other drugs. Share a list of all medications you are using including all prescriptions, non-prescriptions and herbal supplements with your doctor to help monitor possible interactions.
Below is a list of drugs that may interact with Arduan.
- Activated charcoal
This is not a complete list of all drugs that interact with Arduan even though your doctor may be monitoring the interactions on your behalf.