Brand Name(s): Emend
Drug Class: Antiemetics
Treats: Nausea, chemotherapy side effects
Aprepitant is known to be highly effective in preventing vomiting and nausea that are caused by cancer medications. Aprepitant is not used alone and is a part of medication when one goes under surgery or is under severe medication process.
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Aprepitant is a medication that is used to prevent vomiting and using in patients who are undergoing chemotherapy. Aprepitant may be used for situations when medication in patients suffering from cancer creates unwanted effects. Aprepitant is also sometimes used to work after surgery for preventing nausea and vomiting. The Aprepitant works by blocking neurokinin one which is body's natural substance and is known to cause vomiting. Aprepitant has no effect on nausea or vomiting cases if one is already suffering from it. Aprepitant may have a lot of other uses that are not mentioned on the label.
- Chemotherapy side effects (Nausea and Vomiting)
Aprepitant dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Follow your medical professional's directions for best results.
- Aprepitant is taken by patients generally one hour before the session of chemotherapy.
- 125 mg of medication is advised, it may be changed in some situations when the patients needs and reaction to the medication are different.
- On consequent days of therapy sessions 80 mg of medication is given to the patient.
The medication should be closely administered on day one and the experts should be around when the medication is consumed.
Aprepitant Side Effects
Aprepitant side effects may not be completely mentioned here. There may be more side effects to the medication than the ones mentioned here. Aprepitant is known to be highly reactive and any sedative that is taken should be closely monitored with the medication in order to ensure that the patients are safe. It is advised that anything disturbing is brought to the doctor's attention immediately:
- Black or tarry stools
- lower back or side pain
- pale skin
- sore throat
- unusual bleeding or bruising
- Blistering, peeling, or loosening of the skin
- unusual tiredness or weakness
- joint or muscle pain
- painful or difficult urination
- shortness of breath
- ulcers, sores, or white spots in the mouth
- confusion about identity, place, and time
The patients must be closely monitored when under the dose and any persistent side effects must be immediately addressed by the doctors.
Like any other drug, Aprepitant may interact with other drugs and substances. You should consult with your doctor or medical professional before adding any new medication, including over the counter drugs. Below is a list of drugs that have been known to interact with Aprepitant. Note that this list does not include all possible drug interactions.
- Acetaminophen-odan (acetaminophen)
- Acetylsalicylic Acid (aspirin)
- Aprodine (pseudoephedrine / triprolidine)
- Avastin (bevacizumab)
- Carboplatin Novaplus (carboplatin)
- Clotrimazole Troche (clotrimazole)
- Cyclafem 7 / 7 / 7 (ethinyl estradiol / norethindrone)
- Eligard (leuprolide)
- Lupron (leuprolide)
- Polysaccharide Iron (iron polysaccharide)
- Zoladex (goserelin)
- Zofran (ondansetron)
- Herceptin (trastuzumab)
- Demerol (meperidine)
- Casodex (bicalutamide)
- Bactrim DS
- Alprazolam Intensol (alprazolam)
All the herbal and non-herbal medication that are taken must be made known to the doctors so that they can judge the dosage appropriately and ensure that the patients are getting the desired dose.