Brand Name(s): Iopidine
Drug Class: Ophthalmic glaucoma agents
Apraclonidine HCL is an alpha-adrenergic agonist. Apraclonidine HCL is used to prevent or control high fluid pressure within the eyes for those patients who are already under other medications and may need further lowering of the pressure in the eye. Apraclonidine HCL works by decreasing fluid formation in the eye and this assists in lowering the pressure inside the eye.
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Apraclonidine HCL Uses
Apraclonidine HCL is used with other medications to treat serious high pressure in the eye that is glaucoma for a short period of time. Apraclonidine HCL helps in preventing or delaying the need for eye surgery. It is important to note that decreasing the high pressure inside the eye may be of great help because it may help to prevent blindness or decreased vision. Apraclonidine HCL is believed to work by decreasing the amount of fluid that is found within the eye.
Apraclonidine HCL Dosage
You will find the basic dosage below that is used by most doctors to give Apraclonidine HCL is to their patients. However, a physician might prescribe a different regimen depending on your medical condition and history for Apraclonidine HCL. You should not stop, change your dosage, or start taking your medication without consulting your Physician.
Adult Dose for Glaucoma
- Use 1 to 2 drops (0.5%) in each affected eye 3 times a day
Adult Dose for Postoperative Increased Intraocular Pressure
- Use 1 drop (1%) into the scheduled operative eye 1 hour before initiating anterior segment laser surgery and 1 drop (1%) into the same eye immediately postoperatively.
Renal Dose Adjustments
- Close monitoring of cardiovascular status is advised in patients who have renal impairment.
Liver Dose Adjustments
- Close monitoring of cardiovascular status is advised in patients with hepatic impairment.
Apraclonidine HCL Side Effects
Like any medication, Apraclonidine HCL has its side effects and in the case where they develop, contact your pharmacist or doctor as soon as possible. On your healthcare provider can advise on whether it is safe to continue taking Apraclonidine HCL.
For 0.5% Apraclonidine HCL
- More common side effects of Apraclonidine HCL include:
- Allergic reaction (redness, itching, tearing of eye)
Less common or rare side effects of Apraclonidine HCL
- raising of upper eyelid
- wheezing or troubled breathing
- numbness or tingling in fingers or toes
- chest pain
- irregular heartbeat
- Blurred vision or change in vision
- eye discharge, irritation, or pain
- rash around eyes
- clumsiness or unsteadiness
- swelling of face, hands, or feet
For 1% Apraclonidine HCL
Less common or rare side effects of Apraclonidine HCL include:
- Allergic reaction (redness of eye or inner lining of eyelid, swelling of eyelid, watering of eye)
- irregular heartbeat
Apraclonidine HCL Interactions
Drug interactions may increase the risk of serious side effects or may alter how your medications work. It is advisable to keep a list of all the medications that you use including non-prescription and prescription drugs and share the information with your doctor or pharmacist. Some products that may interact with Apraclonidine HCL include:
- Advair Diskus (fluticasone / salmeterol), Ambien (zolpidem)
- Cordarone (amiodarone), Coumadin (warfarin)
- Cymbalta (duloxetine), Diltiazem Hydrochloride CD (diltiazem)
- Diphenadryl (diphenhydramine), K-Dur (potassium chloride)
- Klor-Con M20 (potassium chloride), Lantus (insulin glargine)
- Lasix (furosemide), Lipitor (atorvastatin)
- Plavix (clopidogrel), Vitamin D3 (cholecalciferol)
- Promethazine VC Plain (phenylephrine / promethazine)
- Urecholine (bethanechol), Vitamin B1 (thiamine)