Generic Name(s): Sodium hyaluronate ophthalmic
Drug Class: Ophthalmic surgical agents
Treats: Surgical aid during eye surgery.
Amvisc is a solution of sodium hyaluronate that is usually sterile and non-pyrogenic. Amvisc has 16 mg of sodium hyaluronate that is mixed with physiological sodium chloride phosphate that acts as a buffer solution (pH 6.8-7.6). Sodium hyaluronate functions as a lubricant that plays a vital role in managing interactions between adjacent tissues.
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Amvisc is administered for use as a surgical medicine in ophthalmic anterior together with posterior segment surgery including cataract extraction, intraocular implantation, corneal transplantation and glaucoma filtering surgery and surgical procedure to attach a detached retina.
Amvisc is also used to help in maintaining the depth of the anterior chamber and discernibility, minimizing contact between tissues, and functions like a tamponade and vitreous alternative when the reattachment of the retina is being done.
- Ophthalmic anterior surgery
- Posterior segment surgery
- Cataract extraction
- Intraocular implantation
- Corneal transplantation
- Glaucoma filtering surge
- Surgical procedure to attach a detached retina
An Amvisc injection is the most common form, and a medical professional will normally give this to you. Your doctor makes the final decision on what dosage you need depending on factors such as your needs.
- Amvisc is supplied in disposable glass syringes containing either 0.5 ml or 0.8ml of sodium hyaluronate. Sodium hydroxide and in some cases hydrochloric acid is added to adjust ph if deemed appropriate. For intraocular use keep at 2 to 8 degrees Celsius and protect from freezing.
Amvisc Side Effects
Amvisc is in most cases well tolerated but can cause many different side effects. Sodium hyaluronate being naturally in the tissues of the body is well tolerated by the body. It is important to tell a health-care professional concerning any side effects so that you can be monitored. If you suffer a side reaction please contact your doctor as soon as possible. Depending on the severity of the reaction, your doctor may adjust your dose or even discontinue the administration of the medicine. These side effects can be reported to the FDA, and they include:
- Corneal edema
- Corneal decompensation
- Increased pressure in the eye
- Inflammation of the iris
- White blood cells in the front of the eye
- Difficulty swallowing
- Skin rash
- Stuffy nose
- Swelling of lips
- Tightness in chest
- Loss of appetite
- Stomach pain
Some drugs are likely to interact with Amvisc. Interactions are known to increase the likelihood of side effects. You should consult a health-care for specific guidance if you are taking any prescription or non-prescription drugs. The following medicines may interact with Amvisc:
- Ascorbic acid
- Vitamin B Complex 100