Brand Name(s): Campath, MabCampath, Campath-1H, Lemtrada
Drug Class: cd52-directed cytolytic antibody
Treats: b-cell chronic lymphocytic leukemia
Alemtuzumab is used in the treatment of a certain type of leukemia known as the B- cell, Chronic Lymphocytic Leukemia (B-CLL). Alemtuzumab is also used in the treatment of a certain type of multiple sclerosis. Alemtuzumab is a prescription drug, thus it is only used under the direction of a doctor or physician.
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Alemtuzumab works by inhibiting the growth and multiplication of cancer cells. While Alemtuzumab is not a cure for multiple sclerosis, it is believed that it plays a vital role in preventing the immune system cells (lymphocytes) from attacking the nerves in the brain and the spinal cord. Alemtuzumab helps reduce the occurrence of episodes that may worsen, prevent or delay disability. Inform your doctor if you have thyroid, bone marrow, immune and kidney, as well as blood problems, before using Alemtuzumab. Also, let the doctor know if you have a history of tuberculosis, hepatitis, mental or mood problems.
- Chronic Lymphocytic Leukemia (B-CLL)
- Multiple sclerosis.
Use Alemtuzumab as directed by the doctor. If you are using Alemtuzumab for self-treatment, ensure that you read the dosage information on the drug's label carefully. Alemtuzumab dosage will be different from one individual to the other depending on the severity of the condition being treated. Also, the patient's weight, medical history, height and response to treatment may determine the dosage.
- Alemtuzumab dose is administered slowly, thus the needle will remain in place for about 2 hours. The injection administered once every 24 hours for a period of 3 to seven days. The dose is then changed to 3 days every 7 days for up to 12 weeks.
Since Alemtuzumab is used as need, call you doctor for instructions on what to do if you miss a dose.
Alemtuzumab Side Effects
Just like all medicines, Alemtuzumab causes side effects. Some of the patients may experience the side effects while others may not. Check with your doctor if the following common side effects become persistent or do not go away
Call your doctor immediately if you experience the following severe side effects
- Shortness of breath
- White patches in the mouth
- Yellowing of the skin and eyes
- Irregular heartbeat
This is not a complete list of all the side effects that may occur. Contact your doctor if you experience unusual side effects.
Use Aldesleukin as directed by the doctor. The Aldesleukin dose will differ from one patient depending on the severity of the condition being treated. The patient's age, weight, height, past medical history and the response to treatment may also determine the dosage. The amount of Aldesleukin to be used depends on the strength of the medicine.
- Aldesleukin dosage in adults, 0.037 mg/kg by five infusion, every eight hours. The doctor may evaluate the dosage after four weeks depending on the body's response to treatment.
- Aldesleukin use and dosage in children is only determined by the doctor.
If you miss an Aldesleukin dose, use it as soon as you remember. However, if it is time for the subsequent dose, skip the missed dose and go back to the normal schedule.