Generic Name(s): Fluorouracil
Drug Class: Antimetabolite
Treats: Colon cancer, rectal cancer, Breast cancer, Gastrointestinal cancer, Head and neck cancer, Ovarian cancer.
Adrucil, also referred to as fluorouracil, is an antimetabolite that works by interfering with the production of proteins essential for cell growth and reproduction. It exerts its anti-cancer effect by preventing the synthesis of RNA and DNA in the cell by decreasing thymine (a nucleotide that is a building block of DNA). Lack of DNA and RNA helps prevent the cancer cell from further reproducing or making important proteins, which may result in death of cells. This way, Adrucil slows the growth of cancer cells in your body.
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Adrucil is used to treat certain types of cancer, specifically cancer of the colon, rectum, stomach, breast, or pancreas. It is referred to as a chemotherapy drug, and is used in combination with other medications to slow/stop the growth of cancer cells. Similarly, this medication is used as a topical cream in basal cell cancer of the skin and actinic keratosis. This medicine should not be used if you have bone marrow depression that is a serious infection. Similarly, don't use this medicine if you are malnourished or if you have not received proper nutrition.
Below you will find the different uses for Adrucil:
- Colon cancer
- Rectal cancer
- Breast cancer
- Gastrointestinal cancer
- Head and neck cancer
- Ovarian cancer
Adrucil dosage is dependent on the individual that it is being administered to. The following dosage is an average dose and could differ among individuals. Do not take a larger dose or more frequent doses without approval from your doctor. Follow your medical professional's directions carefully for best results.
- 450-600 mg/sq.meter IV weekly, not to exceed 800 mg/day
Adrucil Side Effects
Adrucil, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Adrucil, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
- Stomach cramps
- Chest pain
- Loss of appetite
- Skin rash
- Shortness of breath
- Blood in urine
Below you will find a list of drugs and substances that interact with Adrucil. As with all drugs, before taking Adrucil, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. Do not let anyone else take your medication, and consult your physician before taking any new medication. Note that this list is not complete.