Adcirca is a medicine used in the treatment of pulmonary hypertension. It is also used to improve the exercise capacity in individuals. The active pharmaceutical ingredient of the medicine is tadalafil, which functions in the body as a PDE5 inhibitor. This means the drug causes blood vessel dilation which, in turn, helps to resolve pressure in the lungs. However, this dilation occurs throughout the entire body, meaning hypotension remains a real risk. This is why the drug should be avoided in patients who have cardiovascular disease and who are already taking antihypertensive medication.
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Adcirca is used in the treatment of pulmonary arterial hypertension. It belongs to the drug class known as PDE5 Inhibitors. This drug may be used for purposes not mentioned here, as determined by your doctor.
- Pulmonary Arterial Hypertension
It"s worth noting that the following doses are not fixed and, instead, depend on the nature of the complaint, its severity, and whether the patient has any complicating factors such as disease or co-administration of other interacting drugs. However, the following values are considered the typical dose of Adcirca.
- Pulmonary Hypertension Adult Dose : 40mg to be taken once daily.
Adcirca Side Effects
The vast majority of patients taking Adcirca experience little to no side effects. It is a widely tolerated drug in this regard. However, a small proportion of patients may complain of mild to moderate symptoms, the most important of which are listed below. If you are in any way concerned about these effects, you should consult your healthcare provider at the first opportunity.
- Back Pain
- Flu-like Symptoms
- Hypotension Priapism
- Hearing Loss
- Vision Loss
Adcirca should not be taken with alcohol as this may exacerbate the side effect profile. Patients are also advised to limit, or avoid, consumption of grapefruit juice for the same reason. There are numerous important clinical interactions with Adcirca, some of which are listed below. Consult your doctor or pharmacist if you are in any way concerned about a potential interaction.
- HIV Medication
- Antihypertensive Drugs
- Azole Drugs
- Grapefruit Juice
- Protease Inhibitors