Abiraterone is used to treat prostate cancer that has metastasized, or spread beyond its original location. The drug works by blocking the effects of the male hormone androgen in the body. It is used in combination with prednisone.
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Abiraterone is prescribed to an individual suffering from advanced prostate cancer. Prostate cancer symptoms include trouble with urination, blood in the urine, erectile dysfunction, and others.
Prostate cancer latches on to androgens, which are produced by the CYP17 enzyme. Lowering the androgens can prevent prostate cancer from spreading. Abiraterone is a CYP17 inhibitor that helps to block the enzyme and lowers the androgen levels in the individual. It may not be appropriate for people with liver disease, heart disease, low potassium levels, high blood pressure or any type of infection.
Below you will find the different uses for Abiraterone:
- Prostate Cancer
Abiraterone dosage is completely dependent on the individual that takes it, as it can be used for a variety of conditions. Note that the amount of Abiraterone you also take depends on the age of the individual. In addition, the amount of Abiraterone you take also depends on the strength of the inhaler and the amount of times you plan on using the inhaler. Abiraterone dosage also depends on the type of condition you are treating.
The following dosage is an average dose and could differ among individuals. Do not take a larger dose or more frequent doses without approval from your doctor. Follow your medical professional's directions carefully for best results.
- Abiraterone is prescribed only for adults.
- The dose is typically 1000 mg taken by mouth once a day, in combination with 5 mg of prednisone taken by mouth twice a day.
- If the liver does not appear to be tolerating the therapy,the drug should be stopped altogether, then reinstated at a dose of 750 mg per day once after liver function has returned to normal.
Abiraterone Side Effects
Abiraterone, like any other drug, comes with its collection of side effects that vary with each individual who uses it. When you first begin taking Abiraterone, watch yourself carefully for any worrying reactions. If you experience any severe side effects, consult with your doctor or medical professional immediately. Below is a list of known side effects. Note that this list is not complete.
- swelling, particularly in the face or extremities
- blurred vision
- dizziness or fainting
- dry mouth or increased thirst
- dark, bloody or cloudy urine
- an increase in urinary frequency
Other, less serious side effects may include:
Below you will find a list of drugs and substances that interact with Abiraterone. As with all drugs, before taking Abiraterone, you should make your doctor aware of any medications you may be taking, including prescription and over-the-counter drugs, as well as supplements and herbal remedies. You should also let your doctor know if you are pregnant or breastfeeding, and if you have any allergies to drugs or foods. Do not let anyone else take your medication, and consult your physician before taking any new medication. Note that this list is not complete.
Abiraterone may not be appropriate for people with liver disease, heart disease, low potassium levels, high blood pressure or any type of infection. It may also interfere with existing problems of the adrenal and pituitary glands.
Abiraterone has known interactions with more than 370 drugs.Some of the most serious include: