Thyroxines Drug Class

Thyroxines are hormones generated by the thyroid gland and the most common thyroid hormones. Thyroxines structure is attached four molecules of iodine. Thyroxines affect most of the body functions such as temperature, growth and heart rate. Thyroxine is secreted by the follicular cells of the thyroid gland. Thyroxine is used to treat thyroid hormone deficiency and sometimes prevent the recurrence of thyroid cancer. Thyroxine works by lowering thyroid stimulating hormone.

Thyroxines Drugs

Some of the drugs found in thyroxine class that are used to perform same functions as thyroxine are available. The use of these drugs is almost the same as the use of thyroxine. There might be a slight difference in the regimen prescribed by the doctors; care should be taken when using these drugs to avoid related side effects. Some of these medicines may include:

  • L-thyroxine
  • levothyroxine
  • Synthroid
  • Thyrax
  • thyroxin
  • Thyro Tabs
  • Thyreoidea
  • Thyroxine iodine
  • Tetraiodothyronine
  • Levothyroxine
  • 3,3′,5,5′-Tetraiodo-L-thyronine
  • L-Thyroxine
  • Thyroxine (l)
  • Levothroid
  • Levoxyl
  • 3,5,3′,5′-Tetraiodo-L-thyronine
  • L-T4
  • 51-48-9
  • Levothyroxine
  • Levothyroxine sodium
  • T4

Thyroxines Uses

Thyroxine is employed in the treatment of hypothyroidism. Since Thyroxines can lower thyroid stimulating hormone, it can as well be used to treat goiter. Some signs of activities that may result in these defects in question are nervousness, tremor, increase blood pressure and palpitations. Thyroxine is used as intervention therapy in patients with nodular thyroid cancer by suppressing thyroid – stimulating hormone secretion. Thyroxine increase basal metabolic rate, affect protein synthesis and help regulate long bone growth. Thyroxine also stimulates vitamin metabolism and regulates protein, fat, and carbohydrate metabolism.

Thyroxines Side Effects

Dosing of thyroxine should be controlled within the normal reference range. Long-term suppression of Thyroid Stimulating Hormone values below normal will cause cardiac effect. Overdose and underdose may result in severe side effects. You should check with your doctor immediately if any of these side effects occur when taking thyroxine:

  • Chest discomfort
  • decreased urination
  • difficulty in breathing
  • swallowing problems
  • dilated neck veins
  • severe fatigue
  • fainting
  • irregular heartbeat
  • fever
  • heat intolerance
  • increased blood pressure
  • irritability
  • menstrual changes
  • nausea
  • shortness of breath
  • skin itching, rash, or redness
  • sweating
  • swelling of the face,
  • chest tightness
  • tremors
  • troubled breathing

Thyroxines Interactions

Some foods and other drug substances can interfere with the absorption of thyroxine. Such elements may include calcium and iron supplements as well as soy products that are taken within three to four hours of medication. Grapefruit may delay the absorption of thyroxine in the body. Also, lithium can inhibit the synthesis of thyroxine by affecting iodine metabolism in the body. Coffee may interfere with the intestinal absorption of thyroxine. Combination of thyroxine with ketamine may cause hypertension and tachycardia. Other drug substances may include: