Generic Name(s): denosumab
Drug Class: IgG2 monoclonal antibodies
Treats: osteoporosis, bone loss
Prolia is a prescription medication belonging to a class of drugs known as IgG2 monoclonal antibodies. Prolia is a brand name drug; the generic name of this drug is denosumab. Prolia isu sed to treat bone loss resulting from osteoporosis and menopause. The drug works by decreasing bone resorption and increasing bone mass and strength in several types of bone.
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Prolia is used in the treatment of postmenopausal women with osteoporosis, as well as to increase bone mass in men with osteoporosis. Prolia is used in patients who are at high risk for fracture, have a history of osteoporotic fracture, or patients who have failed or are intolerant to other available osteoporosis therapies and medications. Prolia is used to treat bone loss in men with prostate cancer. Prolia is used in women with breast cancer who are receiving certain treatments that increase their risk for fractures. The drug is also used to reduce fractures from cancers which begin in other parts of the body and subsequently spread to the bones.
Dosing of Prolia will vary amongst patients. The prescribing doctor's orders and directions on the label should always be followed. The amount of Prolia needed depends on the strength, the number of doses taken each day, the time between doses, the length of time taken, and the diagnosis of the patient.
- Usual dosage of Prolia for Adults: 60mg as a single subcutaneous injection once every six months. If a dose is missed, it should be administered as soon as possible, and then scheduled injections should continue every six months from the date of the last injection.
- All patients should receive 1000mg of calcium daily and at least 400 IU of vitamin D daily while receiving Prolia.
Prolia Side Effects
Along with its needed effects, Prolia may cause some unwanted effects. All, some, or none of the possible side effects may occur. A doctor should be consulted with any noted side effects.
- back pain
- upper abdominal pain
- peripheral edema
- upper respiratory tract infection
- pain in extremities
- musculoskeletal pain
- bone pain
- numbness or tingling in the fingers
- or aroundthe mouth
- difficulty breathing or swallowing
- swelling of the face
- or lips
- blurred vision
- fever or chills
- swelling or warmth of skin
- ear drainage or severe pain
- frequent or urgent need to urinate
As with all medications, Prolia possesses the ability to interact when given at the same time as other medications. Drug coadministration should be carefully monitored at all times by a physician who can effectively determine the cost-benefit ratios for each patient. Below is a list of possible drug interactions with Prolia.