Pomalyst (pomalidomide) is an oral immunomodulatory agent (IMiD) that is used in treating multiple myeloma, a condition that results from a progressive blood disease. Pomalyst is administered after a patient has tried out other medications that have not yielded any positive results. Pomalyst affects the immune system by promoting immune response to help in slowing tumor growth.
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Pomalyst is used in treating multiple myeloma, which is a type of cancer in the bone marrow. Pomalyst is only used after a patient has tried out other medications that have not worked (such as bortezomib and lenalidomide). Pomalyst is an immunomodulator and works by stopping or slowing cancer cells growth. Pomalyst can be used with dexamethasone or alone to treat multiple myeloma that has not shown improvement within 2 months of treatment with at least two other drugs. Pomalyst helps kill abnormal cells in the bone marrow and helps the bone marrow produce normal blood cells. Below you will find the uses of Pomalyst.
- Multiple myeloma
Pomalyst can only be issued by a certified pharmacy under the Pomalyst REMS (a special program). The patient's doctor must be registered in the Pomalyst REMS program in order to prescribe. Pomalyst must only be used within Pomalyst REMS guidelines to avoid any exposures to an unborn child. Pomalyst should be taken by mouth without meals as instructed by a medical professional. The capsules should be swallowed whole with water. Patients should not break, crush or open the capsules. In case the capsule gets on a patient's skin, it should be washed immediately. Pomalyst can be absorbed through the lungs and skin and may cause harm to an unborn baby, therefore, those who are pregnant or may become pregnant should not handle Pomalyst. Below you will find a typical dosage of Pomalyst.
- 4 mg once every day at least 2 hours after or before a meal
- This medication is taken days 1-21 in a 28-day cycle
Pomalyst Side Effects
Like any drug, Pomalyst may cause side effects. If you experience severe or persistent side effects, you should contact your doctor. Pomalyst reduces bone marrow function, an effect that can cause a low number of blood cells such as white cells, platelets, and red blood cells. This can lead to anemia or cause easy bleeding or bruising. Sometimes Pomalyst can cause side effects as a result of the speedy destruction of cancer cells (tumorlysis syndrome). Patients should drink plenty of water to lower this risk. Common side effects of Pomalyst are listed below. Note that not all possible side effects are listed.
- Loss of appetite
- Mild rash
- Joint pain
- Muscle pain
- Feeling weak
Contact your doctor if you experience the following:
- Swelling of one's feet or hands
- Chest pain
- Coughing up blood
- Rapid breathing
- Sudden cough
- Swollen gums
- Cold or flu
- Pain during swallowing
- Painful mouth sores
- Skin sores
- Unusual bleeding of the vagina, mouth, nose or rectum
- Easy bruising
- Purple or red spots on the skin<
- Numbness or tingly feeling
- Feeling short of breath
- Trouble concentrating
- Rapid heart rate
- Pale skin
- Feeling light-headed
- Easy bruising
Drug interactions can affect how Pomalyst works. Patients should inform doctors about all drugs under usage. Smoking cigarette can reduce blood levels of this drug. Therefore, a patient should inform the doctor in case they are smoking or if they have recently stopped smoking. Some medications that can cause interactions with Pomalyst include the following. Note that not all possible interactions are listed.