Phosphate binders Drug Class

Phosphate binders are drugs that decrease the absorption of phosphate taken with snacks and meals. Phosphate binders treat chronic kidney heart failure, CKF. They occur in four types that are:

  • Calcium-based phosphate binders
  • Aluminum-based phosphate binders
  • Magnesium-based phosphate binders
  • Calcium-free, aluminum-free phosphate binders.

Phosphate binders assist to remove excess phosphorus from the body through the stool thus lowering quantity of phosphorus getting into the blood. They work in any of the two different ways. First: Some phosphorus binders like Renvela function like a sponge. They soak up the phosphorus found in the food hindering them from getting into the blood. Instead, passed through the alimentary canal and excreted in the stool. Second: Other phosphate binders for example tums, phoslo and fosrenol acts like a magnet. Phosphate binders connect to Phosphates in the food and excreted in the stool.

Phosphate binders Drugs

Drugs that belong to the class Phosphate binders include:

Phosphate binders Uses

Phosphate binders lower phosphate absorbed into the blood. For patients suffering from chronic kidney failure, the control of serum phosphate is essential as this disorder link to bone pathology. Phosphatase inhibitors bind to phosphate in the digestive tract unavailing them for absorption in the blood and later removed from the body in stools. The simple molecular entities, calcium, aluminum, lanthanum and magnesium, bind phosphates in meals to form an insoluble compound. Some other disorders that phosphatase inhibitors treat are:

  • Chronic kidney failure (CKF)
  • Duodenal Ulcer

Phosphate binders Side Effects

Phosphatase inhibitors, just like other medications, may have their unwanted effects. Any unlikely situation you might experience, immediately seek medical attention. The most frequent and severe side effects include:

  • diarrhea,
  • feeling sick
  • Chalky taste in the mouth.
  • Tarry, bloody, or black stools;
  • severe constipation
  • stomach pain
  • fever
  • chills
  • body aches
  • Flu symptoms.

Less serious side effects may include:

  • Nausea
  • vomiting
  • loss of appetite
  • upset stomach, bloating and gas
  • mild constipation and diarrhea
  • tired feeling
  • itching
  • Joint pain

Phosphate binders Interactions

There are various possible interactions with phosphate inhibitors. In the case of drug interactions, don’t start or stop using the drug or even amend the prescribed dosage without consulting your doctor. A few of drugs that cause severe interactions with inhibitors include: