Nicotine Agonists Drug Class

Nicotine Agonists are drugs that prevent acetylcholine (ACh) from using the nicotinic acetylcholine receptors by mimicking them. The drugs are so-called because of their affinity for nicotine. Nicotine Agonists are used to combat dementia, dementia caused by Alzheimer’s disease, addiction to tobacco, glaucoma, and as a muscle relaxant.

Nicotine Agonists Drugs

Below you will find a list of drugs that fall under this class:

Nicotine Agonists Uses

Nicotine agonist medications are used in a number of different medications for diverse uses that include the treatment of dementia caused by Alzheimer’s disease, dependency/addiction to tobacco, glaucoma, and a short-term muscle relaxant.

Research shows that nicotine agonists may also be useful as therapeutic medications for such disorders as schizophrenia and attention-deficit hyperactivity disorder (ADHD).

Nicotine Agonists Side Effects

Below you will some the side effects for the main drugs in the class of Nicotine Agonists:

Carbachol

Possible side effects include:

  • blurred vision
  • brow ache
  • difficulty to see in blurred light
  • and headache

Serious side effects require immediate medical attention including:

  • diarrhea
  • eye pain
  • increased saliva
  • nausea and stomach pain or cramps.

It is rare to experience a serious allergic reaction but in such a case patients are urged to seek medical attention as soon as possible. Side effects indicating such a reaction include:

  • difficulty breathing
  • rash
  • severe dizziness and swelling in the face
  • tongue or throat.

Galantamine

The list of less common side effects is lengthy but the most common side effects experienced include:

  • a decrease in appetite
  • diarrhea and weight loss

Patients experiencing more serious symptoms such as chest pain or irregular heartbeat are advised to seek medical attention right away.

Nicotine

    The most common possible side effects include coughing

  • heartburn
  • indigestion
  • irritation of the mouth and throat
  • nausea
  • stuffy nose
  • upset stomach

Suxamethonium Chloride

possible side effects include:

  • an increase in saliva
  • gastrointestinal problems
  • muscle pain
  • spasms or tenderness.

Varenicline

possible side effects include

  • bizarre dreams
  • change in taste
  • changes in mood or behavior
  • chest pain
  • constipation
  • diarrhea
  • difficulty sleeping
  • dry mouth
  • fatigue
  • gas
  • headache
  • nausea and stomach pain
  • weight gain

There are also a number of less common side effects including changes in

  • appetite
  • difficulty breathing
  • hyperventilation
  • tightness of the chest
  • vomiting and wheezing

Nicotine Agonists Interactions

Nicotine should be avoided while using nicotine agonists and any vitamins or herbal supplements used should first be discussed with a physician. Any mental health issues that may occur including depression should be brought to the attention of a physician immediately. Patients are advised to delay operating motor vehicles until they are aware of how the medication will affect them.

Medications used to stop smoking or using tobacco products are highly recommended to be used in conjunction with such efforts as counseling support, stress management, and lifestyle changes.

Possible drug interactions vary across nicotine agonist drug types but include drugs that impact liver enzymes, adenosine, antibacterials, anticholinergic medications, aspirin, cholinesterase inhibitors, clozapine, heart medications, magnesium salts, NSAIDs, ropinirole, steroids, theophylline and others. Carbachol has specific drug precautions including presenting family history of asthma, eye problems or eye disease, low or high blood pressure, Parkinson’s disease or stomach or urinary problems. Certain inactive ingredients in carvacrol medications may cause allergic reactions such as benzalkonium chloride.

Certain medications may also needed to be adjusted for new dosages after the cessation of smoking including certain asthma medications, insulin, and warfarin.