Also commonly known as, muscarinic receptor agonists, these drugs enhances the performance of the muscarinic acetylcholine receptor; they come in various types with the most common ones categorized into subtypes from M1 to M5- these subtypes features various individual muscarinic receptor agonist drugs. This category of drugs have a very wide range of uses since each type of a subtype has its applications. While subtype M1 drugs, for instance, are known to improve memory and sometimes to learn in case of schizophrenia, M3 subtype drugs- cholinoceptors mostly cause shrinking of the sphincter muscle in the iris and trabecular meshwork and in addition enhance outflow facility of aqueous humour. Again, the effect of M3 drugs in the iris dilator varies from one drug to another but the focal point of each effect is the relaxation of the muscles.
Muscarinic Agonists Drugs
The following list are some of the drugs that fall under this class- the list is not inclusive of all the drugs under the category hence you are advised to seek clarification from your doctor for proper identification of all drugs under this category.
Muscarinic Agonists Uses
As already mentioned, this class of drugs is used in treatment of a variety of illnesses and complications.
- Decrement of depositions of amyloid
- Improvement of damages caused by oxidative stress.
- Enhancement of cholinergic function.
- Treatment of Alzheimer disease.
- Improvement of cognition in patients suffering from Alzheimer disease.
- Treatment of glaucoma
- Managing dry mouth condition in patients with Sjogren ‘s syndrome.
- Treatment of schizophrenia
- In researches where induction of Parkinson’s disease is desired
- Diagnosis of bronchial hyperactivity
- Some act as nutrients
Muscarinic Agonists Side Effects
Even though these drugs fall into the same class, each has their unique way of operation hence if you experience unexpected symptoms or conditions consult your doctor immediately; mistaking one drug under this category for the other can cause side effects such as:
- Decreased heart rate
- Increased secretion of saliva
- Visual problems
- Cramps in the abdomen
- Joint pains
- Excess sweat secretion
- Dryness in the mucous membranes
- Loss of appetite.
Other drugs in this category have their side effects more or less the same as those above and you should consult your doctor about the same.
Muscarinic Agonists Interactions
Apart from interacting with other drugs, muscarinic agonists interact with other conditions as well as a certain kind of diet.
You should not undergo muscarinic agonists drug medications if you suffer the following conditions:
- coronary artery disease
- peptic ulcer disease
Here is a list of some of the drugs known to interact with muscarinic agonists
- ipratropium bromide
During the course of treatment using any drug under this category, the patient is warned to neither smoke nor take alcoholic substances; this may either introduce or accelerate some side effects hence hampering proper and effective treatment